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王连唐

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期刊论文

破骨细胞功能调控与骨质疏松症*

王连唐滕晓英王连唐△

中国病理生理杂志,2002,18(8):1012-1015,-0001,():

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摘要/描述

Osteoclast (OC) are bone resorbing cells whose development and activity are under the in- fluence of osteoblast (OB). The potential association between those two cell lineages is an area of significantinterest. It was not until 1998 that osteoclast differentiation factor (ODF) and osteoprotegerin (OPG) wascloned. The two novel TNF superfamily members have been recently demonstrate to be the key extracellularregulators of osteoclasteogenesis and bone resorption both in vivo and in vitro, and they play important roles inosteoporosis development, diagnosis and treatment

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