Based on the analysis of the disadvantages of traditional methods in reducing pipeline resistance, the new conception of dynamic drag reduction in pipeline transportation has been proposed. The experimental results and mechanism of dynamic reduction of pipeline resistance were also discussed in detail. The main conclusion is that the dynamic reduction of resistanee exerts forces on the moving materials along both the radial direction and the axial direction. The radial force throws the materials upwards to depart from the pipe wall to reduce the frietional force, while the axial force directly reduces the resistance by providing the force to overcome the drag.