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期刊论文
Anti-AIDS Agents Part 41:† Synthesis and Anti-HIV Activity of 3', 4'-di-o-(-)-camphanoyl-(+)-cis-khellactone (DCK) Lactam Analogues
Bioorganic & Medicinal Chemistry Letters 10(2000)1003-1005,-0001,():
DCK lactam analogues were synthesized and evaluated for anti-HIV activity against HIV-1 replication in H9 lymphocyte cells. 4-Methyl-DCK lactam (11a) exhibited potent anti-HIV activity with EC50 and therapeutic index values of 0.00024μM and 119,333, respectively.
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