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期刊论文

SilkDB: a knowledgebase for silkworm biology and genomics

夏庆友Jing Wang Qingyou Xia Ximiao He Mingtao Dai Jue Ruan Jie Chen Guo Yu Haifeng Yuan Yafeng Hu Ruiqiang Li Tao Feng Chen Ye Cheng Lu Jun Wang Songgang Li Gane Ka-Shu Wong Huanming Yang Jian Wang Zhonghuai Xiang Zeyang Zhou and Jun Yu *

Nucleic Acids Research, 2005, Vol. 33, Database issue D399-D402,-0001,():

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摘要/描述

The Silkworm Knowledgebase (SilkDB) is a webbased repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a 6X draft genome sequence of the domestic silkworm (Bombyx mori), SilkDB provides an integrated representation of the large-scale, genome-wide sequence assembly, cDNAs, clusters of expressed sequence tags (ESTs), transposable elements (TEs), mutants, single nucleotide polymorphisms (SNPs) and functional annotations of genes with assignments to InterPro domains and Gene Ontology (GO) terms. SilkDB also hosts a set of ESTs from Bombyx mandarina, a wild progenitor of B.mori, and a collection of genes from other Lepidoptera.Comparative analysis results between the domestic and wild silkworm, between B.mori and other Lepidoptera, and between B.mori and the two sequenced insects, fruitfly and mosquito, are displayed by using B.mori genome sequence as a reference framework. Designed as a basic platform, SilkDB strives to provide a comprehensive knowledgebase about the silkworm and present the silkworm genome and related information in systematic and graphical ways for the convenience of in-depth comparative studies. SilkDB is publicly accessible at http://silkworm.genomics.org.cn.

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