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期刊论文

Design and Synthesis of Guanidinoglycosides Directed against the TAR RNA of HIV-1

杨铭by Min Wang a) Peng-Fei Tu b) Zhi-Dong Xu a) Xiao-Lin Yu a) and Ming Yang*a)

HEL VETICA CHIMICA ACTA-Vol.86 (2003),-0001,():

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摘要/描述

Replication of human immunodeficiency virus type 1 (HIV-1) requires specific interactions of the Tat protein with the transactivation responsive region (TAR) RNA. Tat-TAR RNA Interaction is mediated by a short arginine-rich domain of the protein. Disruption of this interaction could, in theory, create a state of complete viral latency. Here, four novel 6-amino-6-deoxytrehalose guanidinoglycoside derivatives (10 and 13

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版权说明:以下全部内容由杨铭上传于   2005年06月16日 22时41分46秒,版权归本人所有。

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