Using the integral transform and the Cauchy singular integral equation methods, the problem of an interface crack between two dissimilar piezoelectric layers under mechanical impacts is investigated under the permeable electrical boundary condition on the crack surface. The dynamic stress intensity factors (DSIFs) of both mode-I and II are determined. The effects of the crack configuration and the combinations of the constitutive parameters of the piezoelectric materials on the dynamic response are examined. The numerical calculation of the mode-I plane problem indicates that the DSIFs may be retarded or accelerated by specifying different combinations of material parameters. In addition, the parameters of the crack configuration, including the ratio of the crack length to the layer width and the ratio between the widths of two layers, exert a considerable influence on the DSIFs. The results seem useful for design of the piezoelectric structures and devices of high performance.