The inverse structure functions of exit distances have been introduced as a novel diagnostic of turbulence which emphasizes the more laminar regions [1–4]. Using Taylor’s frozen field hypothesis, we investigate the statistical properties of the exit distances of empirical 3D fully developed turbulence. We find that the probability density functions of exit distances at different velocity thresholds ξ v can be approximated by stretched exponentials with exponents varying with the velocity thresholds below a critical threshold. We show that the inverse structure functions exhibit clear extended self-similarity (ESS). The ESS exponents ξ(p, 2) for small p (p < 3.5) are well described byζ(p, 2) = p/2, which derives from the observed approximate universality of the distributions of the exit distances for different velocity thresholds ξ v. The data is not sufficient to reject the hypothesis that monofractal ESS is sufficient to explain the data. In contrast, a measure taking into account the dependence between successive exit distances at a given velocity threshold exhibits clear multifractality with negative dimensions, suggesting the existence of a nontrivial dependence in the time series of exit times.