夏兴华
主要从事表界面分析化学的教学和科研工作。
个性化签名
- 姓名:夏兴华
- 目前身份:
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- 学位:
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学术头衔:
博士生导师
- 职称:-
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学科领域:
物理化学
- 研究兴趣:主要从事表界面分析化学的教学和科研工作。
夏兴华,男,1965年7月生于江苏苏州,南京大学化学化工学院教授,博士生导师。2001年度国家杰出青年科学基金获得者。1986、1989 分别获厦门大学学士和硕士学位,1991-1993获国家教委奖学金在德国波恩大学物理化学研究所作访问学者,1996年获波恩大学理学博士学位,1996-1997在德国慕尼黑国防军大学、1997-1998年在德国马普协会柏林Fritz-Haber研究所、1998-2001在荷兰Utrecht大学Debye研究所从事博士后研究。2001年回国后,任南京大学分析科学研究所副所长,《科学通报》特邀编辑,《自然科学进展》、《物理化学学报》和《化学学报》的编委。近年来主要从事表界面分析化学的教学和科研工作。以原位电化学红外和啦曼光谱、在线电化学质谱、扫描探针等表界面波谱技术,从分子、原子层次上阐明表界面反应与相变动力学机制。研究了电极表面有机小分子的电催化氧化,提出了通用于有机小分子电催化反应机理,建立了吸附金属原子增强催化活性的模型,为筛选低温低碳醇燃料电池中高效抗CO毒性的阳极催化剂指明了方向;通过分析红外谱峰频随电位及所处环境的影响,揭示了吸附水分子与电场的作用机制,提出了测定单晶电极的零电荷电位;以原位扫描探针技术对表面相变动力学机理、金属纳米粒子组装和定位电化学纳米加工等进行了深入的研究,提出了利用非平衡态反应进行纳米加工和电化学技术大规模纳米粒子二维组装的新方法;系统研究了半导体材料的化学刻蚀机理与化学刻蚀表面粗糙的起因,提出了硅微加工中化学反应与电化学氧化反应耦合的新观点,在半导体微加工领域有较多的经验积累,发展了控制表面粗糙和大规模生产多孔硅及硅薄膜传感器的新技术;近期开展了酶、DNA等生物分子间的弱相互作用与表征,有序纳米材料的制备与组装以及在生物传感和电催化方面应用,微流控生物分析等方面的研究,提出了自限制电化学组装生物功能材料超薄膜和微流控芯片制备方法等。研究成果在Acc. Chem. Res., Phys. Rev. Lett., Anal. Chem., J. Phys. Chem. B,Chem. Mater.等刊物发表论文50余篇。目前指导博士后1人,博士研究生11人,硕士研究生8人。主持国家杰出青年科学基金、国家自然科学基金委十五重大项目子课题等8项科研项目。
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主页访问
2405
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成果阅读
405
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成果数
10
夏兴华, Jing-Juan Xu, Ning Bao, Xing-Hua Xia, Ying Peng, and Hong-Yuan Chen *
Anal. Chem. 2004, 76, 6902-6907,-0001,():
-1年11月30日
In this work, we establish an indirect amperometric detection method via mounting a single carbon fiber disk working electrode in the end part of a microchannel. This in-channel configuration for microchip capillary electrophoresis brings about that the potential of the working electrode in the case of electrochemical reduction reaction is coupled by the separation electric field, while the potential of the working electrode in the case of electrochemical oxidation reaction is not coupled by the separation electric field. Such a special performance provides a convenient and sensitive approach for indirectly detecting nonelectroactive analytes that relies on amperometric response of dissolved oxygen in solution and directly detecting electroactive analytes based on their own amperometric response on the carbon fiber electrode. This method has shown its essential importance in the analysis of inorganic cations, biomolecules, and electroosmotic flow rates. Based on preliminary results, a detection limit of 1.0μM for K+and Na+have been achieved.
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夏兴华, F. Y. He
Anal Bioanal Chem (2004) 379: 1062-1067,-0001,():
-1年11月30日
Poly (dimethylsiloxane) microchip capillary electrophoresis with amperometric detection has been used for rapid separation and determination of acetaminophen and its hydrolysate, i.e. p-aminophenol. A Pt ultramicroelectrode with a diameter of 10μm positioned at the outlet of the separation channel was used as a working electrode for amperometric detection. Factors influencing separation and detection were investigated and optimized. Results show that acetaminophen and p-aminophenol can be well separated within 35s with RSD-1 (approximately 0.1fmol) at S/N=3. This method has been successfully applied to the detection of traces of p-aminophenol in paracetamol tablets.
Poly (, dimethylsiloxane),
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夏兴华, D. Zhang
Anal Bioanal Chem (2004) 379: 1025-1030,-0001,():
-1年11月30日
A biocompatible and uniform interface based on silica nanoparticles derivatized with amino groups has been constructed for the effective immobilization and sensitive sequence-specific detection of calf thymus DNA. Atomic force microscopy (AFM) and scanning electron microscopy (SEM) results showed that a monolayer of silica nanoparticles can be formed on a gold electrode under our experimental conditions using cysteine self-assembly monolayer as binder medium. Electrochemical impedance spectroscopy and X-ray photoelectron spectroscopy (XPS) verified the successful immobilization of DNA on silica-nanoparticle-modified gold electrodes. Quantitative results demonstrated that enhanced immobilization of single-strand DNA (ss-DNA) up to 1.6
Silica nanoparticles
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夏兴华, Dai Zhang, Ke Zhang, Yan Li Yao, Xing Hua Xia, * and Hong Yuan Chen
Langmuir 2004, 20, 7303-7307,-0001,():
-1年11月30日
A multilayered glucose biosensor via sequential deposition of Prussian blue (PB) nanoclusters and enzyme-immobilized poly (toluidine blue) films was constructed on a bareAuelectrode using electrochemical methods. The whole configuration of the present biosensor can be considered as an integration of several independent hydrogen peroxide sensing elements. In each sensing element, the poly (toluidine blue) film functioned as both the supporting matrix for the glucose oxidase immobilization and the inhibitor for the diffusion of interferences, such as ascorbic acid and uric acid. Meanwhile, the deposited Prussian blue nanocluster layers acts as a catalyst for the electrochemical reduction of hydrogen peroxide formed from enzymatic reaction. Performance of the whole multilayer configuration can be tailored by artificially arranging the sensing elements assembled on the electrode. Under optimal conditions, the biosensors exhibit a linear relationship in the range of 1
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【期刊论文】A Simple Method for Preparation of Through-Hole Porous Anodic Alumina Membrane
夏兴华, J. H. Yuan, F. Y. He, D. C. Sun, and X. H. Xia *
Chem. Mater. 2004, 16, 1841-1844,-0001,():
-1年11月30日
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夏兴华, D. Zhang, K. Wang, D. C. Sun, X. H. Xia, * and H.-Y. Chen
Chem. Mater. 2003, 15, 4163-4165,-0001,():
-1年11月30日
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夏兴华, Xinghua Xia, *, † Colin M. A. Ashruf, ‡ Patrick J. French, ‡ Joerg Rappich, § and John J. Kelly †
J. Phys. Chem. B 2001, 105, 5722-5729,-0001,():
-1年11月30日
Three types of experiments were used to study the surface chemistry of silicon in alkaline solution: minority carrier injection from a p-n junction electrode, in-situ photoluminescence, and electron transfer to a redox system in solution. The results lead to the conclusion that the surface chemistry and electrochemistry are determined to a large extent by an activated intermediate of the chemical etching reaction of silicon with water. This novel coupling of chemical and electrochemical steps can account for some unusual features of the system, such as a mechanism for anodic oxidation and passivation based on electron injection and the strong influence of a weak oxidizing agent on the surface morphology of chemically etched silicon.
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【期刊论文】Electrochemical Nanostructuring with Ultrashort Voltage Pulses
夏兴华, VIOLA KIRCHNER, XINGHUA XIA, † AND ROLF SCHUSTER *
Acc. Chem. Res. 2001, 34, 371-377,-0001,():
-1年11月30日
The application of nanosecond voltage pulses to electrodes provides three ways to conduct local electrochemistry on the microto nanometer scale. (1) The finite charging time of the doublelayer capacity allows the machining of three-dimensional microstructures. (2) In an electrochemical scanning tunneling microscope, reactions are confined to the tunneling region, due to the depletion of the electrolyte in the tip-surface gap. (3) Ordering processes, following very fast electrochemical reactions, lead to unconventional island patterns on a surface.
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夏兴华, X. H. Xia a and J. J. Kelly *
Journal of The Electrochemical Society, 148 (5) C348-C352 (2001),-0001,():
-1年11月30日
Electrochemical reduction of hypochlorite (OCl-) at silicon in alkaline solution occurs via a two-step mechanism. The first step involving a conduction band electron gives an intermediate which subsequently injects a hole into the valence band. As a result, photocurrent doubling is observed with the p-type semiconductor. OCl-reacts chemically with silicon at a rate which is constant for potentials more negative than the open-circuit value. It is shown that OCl-can be used to control the surface morphology of silicon during chemical etching in alkaline solution. In addition, OCl-is a suitable oxidizing agent for achieving a galvanic etch stop in beam and membrane fabrication.
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【期刊论文】Galvanic Cell Formation in Silicon/Metal Contacts: The Effect on Silicon Surface Morphology
夏兴华, X. H. Xia, *, † C. M. A. Ashruf, ‡ P. J. French, ‡ and J. J. Kelly†
Chem. Mater. 2000, 12, 1671-1678,-0001,():
-1年11月30日
When p-type silicon is contacted to a noble metal in HF solution containing an oxidizing agent, a galvanic cell can be formed. The oxidizing agent is reduced at the metal and the semiconductor is etched. To achieve a similar effect with n-type silicon, illumination is required. On the other hand, a galvanic cell is formed with both n-and p-type silicons in alkaline solution in the dark. These results are explained on the basis of silicon electrochemistry with the use of energy band diagrams. It is shown that "galvanic etching" can be used to control the silicon surface morphology, e.g., to form microporous or macroporous layers or produce pyramid-free anisotropic structures.
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