周天寿
(1)系统生物学;(2)生物信息学;(3)混沌控制与反控制。
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- 姓名:周天寿
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学术头衔:
博士生导师
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学科领域:
应用数学
- 研究兴趣:(1)系统生物学;(2)生物信息学;(3)混沌控制与反控制。
周天寿,男,江西新建人,1962年生。2001年获中国科学院数学与系统科学研究院博士学位,1991年获北京大学数学系计算数学专业硕士,1984年获江西师范大学数学系学士学位。2002年8月至2004年8月,获日本科学促进会(JSPS)资助,金沢大学计算数学系博士后;2001年9月至2003年8月,于清华大学数学科学系博士后。2004-现在,中山大学数学与计算科学学院工作。百人计划入选者。2003年获全国百篇优秀博士论文奖(激励介质的非线性波型动力学),2008年获国家自然科学二等奖(混沌反控制与 Lorenz系统族的理论)。中山大学“985工程”创新平台二级PI。广东省工业与应用数学学会副理事长。两个国际刊物的编委。2008-2011,主持国家重点基金(工程基因调控网的设计、构造、建模与分析)。
研究方向:(1)系统生物学;(2)生物信息学;(3)混沌控制与反控制。主要成果:(1) 解决了美国J.J.Tyson教授于1979年提出的一个猜想;(2) 基于生物基因工程技术,建立起多细胞基因通信系统的理论模型,并刻画了外部噪音在细胞通信中的作用,相应的结果发表在Physical Review Letters,95(2005),178103,并且全文被Virtual Journal of Biologically Physical Research转载。特别是,该论文由哈拂大学J.Paulsson教授在Nature上作特别介绍;(3) 给出了一种找Shilnikov型同宿轨或异宿轨的代数方法;首次把三维自治多项式型的ODE系统中的混沌分为四大类:Shilnikov同宿轨型的混沌;Shilnikov异宿轨型的混沌;Shilnikov混合型的混沌和非Shilnikov型的混沌,为系统研究混沌奠定了基础;(4) 在SCI刊物发表或接受发表论文60篇,SCI论文引用超过200次;(5) 2004年获国家专利一项。
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451
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成果数
16
【期刊论文】External stimuli mediated collective rhythms:Artificial control strategies
周天寿
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-1年11月30日
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28浏览
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【期刊论文】Noise-induced switches in network systems of the genetic toggle switch
周天寿
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-1年11月30日
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24浏览
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【期刊论文】Architecture-Dependent Robustness and Bistability in a Class of Genetic Circuits
周天寿
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-1年11月30日
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25浏览
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周天寿, Tianshou Zhou, , * Luonan Chen, † and Kazuyuki Aihara, ‡
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-1年11月30日
We model a synthetic gene regulatory network in a microbial cell, and investigate the effect of noises on cell-cell communication in a well-mixed multicellular system. A biologically plausible model is developed for cellular communication in an indirectly coupled multicellular system.Without extracellular noises, all cells, in spite of interaction among them, behave irregularly due to independent intracellular noises. On the other hand, extracellular noises that are common to all cells can induce collective dynamics and stochastically synchronize the multicellular system by actively enhancing the integrated interchange of signaling molecules.
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41浏览
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【期刊论文】A mechanism of synchronization in interacting multi-cell genetic systems
周天寿, Tianshou Zhou a, ∗, Luonan Chen b, Ruiqi Wang c
Physica D 211(2005)107-127,-0001,():
-1年11月30日
We investigate a general coupled noisy system with time delays, which may be applied to biologically plausible systems for cell-cell communication in a simplified context. The main conclusion is that appropriate noise intensities and coupling strengths are capable of driving the system to be synchronous. We first provide an analytical treatment for the synchronization process, based on the essential phase-locking mechanism, and then derive sufficient conditions which, if satisfied, ensure existence of the synchrony solution. Finally, a multi-cell system with a synthetic gene regulatory network, which contains both intracellular and extracellular noises and time delays, is adopted to demonstrate effects of extracellular noises and couplings on synchronization.
Synchronization, Gene regulatory network, Stochastic differential equation, Global Hopf bifurcation theorem
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21浏览
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【期刊论文】Excitation functions of coupling
周天寿, Tianshou Zhou*, Luonan Chen† and Ruiqi Wang
PHYSICAL REVIEW E 71, 066211 (2005),-0001,():
-1年11月30日
The responses of nonlinear dynamics of two classes to coupling are investigated. It is shown both analytically and numerically that coupling has an excitation ability in a network of the linearly coupled systems. That is, when an uncoupled system is degenerated to a stable steady state from a limit cycle but in the "marginal" state due to the system parameter, an appropriate coupling strength can excite the limit cycle such that the coupled systems exhibit synchronous oscillation; when the uncoupled system is in a stable limit cycle but close to a chaotic attractor, a certain coupling strength can induce the chaotic attractor such that the coupled systems reach chaotic synchronization. Such excitation functions of coupling are different from its traditional role where coupling mainly synchronizes the coupled systems with the original dynamics of the uncoupled system.
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【期刊论文】Synchronization in fractional-order differential systems
周天寿, Tianshou Zhou a, *, Changpin Li b
Physica D 212(2005)111-125,-0001,():
-1年11月30日
An ω-symmetrically coupled system consisting of identical fractional-order differential systems including chaotic and nonchaotic systems is investigated in this paper. Such a coupled system has, in its synchronous state, a mode decomposition by which the linearized equation can be decomposed into motions transverse to and parallel to the synchronous manifold. Furthermore, the decomposition can induce a sufficient condition on synchronization of the overall system, which guarantees, if satisfied, that a group synchronization is achieved. Two typical numerical examples, fractional Brusselators and the fractional Rossler system, are used to verify the theoretical prediction. The theoretical analysis and numerical results show that the lower the order of the fractional system, the longer the time for achieving synchronization at a fixed coupling strength.
Fractional differential equation, Synchronization, Mode decomposition
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