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2012年04月09日

【期刊论文】SWItch/sucrose nonfermentable (SWI/SNF) complex subunit BAF60a integrates hepatic circadian clock and energy metabolism

刘畅, Tao, W., Chen, S., Shi, G., Guo, J., Xu, Y., & Liu, C.

Hepatology (2011), 54: 1410-1420.,-0001,():

摘要

暂无

关键词: circadian clock,, metabolism,, BAF60a,, chromatin remodeling,, liver

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2009年12月09日

【期刊论文】Multimodality Optical Imaging and 18F-FDG Uptake in Wild-Type p53-Containing and p53-Null Human Colon Tumor Xenografts

王树林, Shulin Wang, Akiva Mintz, Kenjiro Mochizuki, Jay F. Dorsey, Joseph M. Ackermann, Abass Alavi, Wafik S. El-Deiry*

Cancer Biology & Therapy (2007) 1-5,-0001,():

摘要

暂无

关键词: p53,, glycolytic metabolism,, Warburg effect,, FDG-PET imaging,, cancer,, bioluminescence imaging,, fluorescence imaging,, PET-CT

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  • 264下载

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2011年10月30日

【期刊论文】Analysis of expressed sequence tags from biodiesel plant Jatropha curcas embryos at different developmental stages

徐增富, Mao-Sheng Chen, Gui-Juan Wanga, Ru-Ling Wang, Jun Wang, Song-Quan Song, Zeng-Fu Xu

Plant Science 181 (2011) 696– 700,-0001,():

摘要

暂无

关键词: Bioenergy plant,, Embryo,, Expressed sequence tags,, Lipid metabolism,, Physic nut,, Seed development

  • 8浏览

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2006年08月04日

【期刊论文】INTERACTIONS OF Na+, H2O2 AND THE Na+-Ca2+ EXCHANGER STIMULATE Ca2+ RELEASE IN CK1.4 CELLS

方琰, Yan Fang, * Mingyang Rang† and Lianfang He†

Chinical and Perimental Pharmacology and Physiology (1997) 24, 170-174,-0001,():

摘要

暂无

关键词: words, calcium metabolism,, cations,, freee radicals,, membrane protein physiology.,

  • 26浏览

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2006年01月06日

【期刊论文】Proteomic Analysis in the Early Process of Pancreatic Regeneration in the Pancreatectomized Rat

黎明涛, Ming YANG*, Cun-you WAGN, Feng ZHOU, Jing TAO, Tao LIU, Hai-yan WEI, Wei LIU, Ming-tao LI, Xian-song FENG

,-0001,():

摘要

暂无

关键词: Partial pancreatectomy,, Regeneration,, Metabolism,, Stem cell,, Pancreas proteomics

  • 31浏览

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  • 161下载

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2005年05月18日

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2010年03月19日

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2005年03月08日

【期刊论文】83-1除草剂在大鼠体内的代谢研究

喻凯, 孙棉龄, 吴德生, 罗永义, 孙爱民

四川环境,1993,12(4):43~47,-0001,():

摘要

目前,我国对新农药的登记要求对其进行代谢降解研究。为此本文采用HPLC、UV、IR 和MS等现代仪器分析的方法,给大鼠经口染毒83-1除草剂后,在大鼠司法尿中分离和鉴定出四种代谢代物,发现该除草剂在大鼠体内的代谢主要是还原和结合作用。从而推断了该农药在大鼠体内的代谢转化过程。

关键词: 83-1除草剂, 代谢 高效液相色谱

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2005年02月25日

  • 19浏览

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2021年05月10日

【期刊论文】Cloning, purification and characterisation of cytosolic fructose-1,6-bisphosphatase from mung bean (Vigna radiata)

Lin Chen, Hongshun Yang, Lin Chen, Hongshun Yang, Lin Chen, Hongshun Yang, Lin Chen, Hongshun Yang

Food Chemistry,2021,-(347):128973

2021年05月10日

摘要

To improve the crop yield and quality, the cytosolic fructose-1,6-bisphosphatase (cFBPase) from mung bean (Vigna radiata), a rate-limiting enzyme in gluconeogenesis, was cloned, purified, and structurally characterised. To function it required Mg2+ and Mn2+ at 0.01–10 mM. The Michaelis-Menton constant and adenosine monophosphate (AMP) inhibitory constant (Ki) were 7.96 and 111.09 μM, respectively. The functional site residues of AMP binding (Arg30, Asp32, and Phe33) and the active site residues (Asn218 and Met251) were tested via site-directed mutagenesis and molecular docking. Asn218 and Met251 were replaced by Tyr and Leu, respectively. The M251L mutant showed enhanced substrate affinity and activity, resulting from decreased binding energy (–2.58 kcal·mol−1) and molecular distance (4.2 Å). AMP binding site mutations changed the enzyme activities, indicating a connection between the binding and active sites. Furthermore, Ki and docking analysis revealed that Asp32 plays a key role in maintaining the AMP binding conformation.

关键词: Enzymatic properties,, VegetableEnergy metabolism,, Site-directed mutagenesis,, Molecular docking,, Simu

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2021年06月14日

【期刊论文】 Energy regulated nutritive and antioxidant properties during the germination and sprouting of broccoli sprouts (Brassica oleracea var. italica)

Yang Hongshun, Chen Lin, Yang Hongshun, Chen Lin

Agricultural and Food Chemistry,2018,-(66):6975-6985

2018年07月12日

摘要

The role of energy status in germination and sprouting of broccoli seeds was investigated by exogenous ATP and DNP treatments. With the synthesis of adenylates from 38.82 to 142.69 mg • 100 g-1 DW, the nutritive components (soluble sugar, proteins, pigments and phenolics) and AAs were increased during germination and early sprouting (day 5). Elements of BoSnRK2 pathway were down-regulated by more than 2 folds under the energy charge feedback inhibition. At the end of sprouting (day 7), energy depletion resulted in slowdown or reduced nutritional accumulation and antioxidant capacities. Exogenous ATP depressed the BoSnRK2 pathway by maintaining the energy status at high levels and further promoted the nutrition and antioxidant levels. It also prevented the energy depletion at day 7. On the contrary, DNP reduced the ATP contents (16.10-26.86%) and activated the BoSnRK2 pathway. It also notably suppressed the energy-consuming activities including germination, sprouts growth and secondary metabolic synthesis.

关键词: antioxidant capacity,, ATP,, metabolism,, transcriptional regulation,, vegetable

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