The genome-wide association study (GWAS) is a popular approach to identify disease-associated genetic factors for Alzhemer's Disease (AD). However, it remains challenging because of the small number of samples, very high feature dimensionality and complex structures. To accurately identify genetic risk factors for AD, we propose a novel method based on an in-depth exploration of the hierarchical structure among the features and the commonality across related tasks. Specifically, we first extract and encode the tree hierarchy among features; then, we integrate the tree structures with multi-task feature learning (MTFL) to learn the shared features-that are predictive of AD-among related tasks simultaneously. Thus, we can unify the strength of both the prior structure information and MTFL to boost the prediction performance. However, due to the highly complex regularizer that encodes the tree structure and the extremely high feature dimensionality, the learning process can be computationally prohibitive. To address this, we further develop a novel safe screening rule to quickly identify and remove the irrelevant features before training. Experiment results demonstrate that the proposed approach significantly outperforms the state-of-the-art in detecting genetic risk factors of AD and the speedup gained by the proposed screening can be several orders of magnitude.

Multi-turn video question answering is a challenging task in visual information retrieval, which generates the accurate answer from the referenced video contents according to the visual conversation context and given question. However, the existing visual question answering methods mainly tackle the problem of single-turn video question answering, which may be ineffectively applied for multi-turn video question answering directly, due to the insufficiency of modeling the sequential conversation context. In this paper, we study the problem of multi-turn video question answering from the viewpoint of multi-stream hierarchical attention context reinforced network learning. We first propose the hierarchical attention context network for context-aware question understanding by modeling the hierarchically sequential conversation context structure. We then develop the multi-stream spatio-temporal attention network for learning the joint representation of the dynamic video contents and context-aware question embedding. We next devise a multi-step reasoning process to enhance the multi-stream hierarchical attention context network learning method. We finally predict the multiple-choice answer from the candidate answer set and further develop the reinforced decoder network to generate the open-ended natural language answer for multi-turn video question answering. We construct two large-scale multi-turn video question answering datasets. The extensive experiments show the effectiveness of our method.

Product reviews are valuable for upcoming buyers in helping them make decisions. To this end, different opinion mining techniques have been proposed, where judging a review sentence's orientation (e.g., positive or negative) is one of their key challenges. Recently, deep learning has emerged as an effective means for solving sentiment classification problems. A neural network intrinsically learns a useful representation automatically without human efforts. However, the success of deep learning highly relies on the availability of large-scale training data. We propose a novel deep learning framework for product review sentiment classification which employs prevalently available ratings as weak supervision signals. The framework consists of two steps: (1) learning a high level representation (an embedding space) which captures the general sentiment distribution of sentences through rating information; and (2) adding a classification layer on top of the embedding layer and use labeled sentences for supervised fine-tuning. We explore two kinds of low level network structure for modeling review sentences, namely, convolutional feature extractors and long short-term memory. To evaluate the proposed framework, we construct a dataset containing 1.1M weakly labeled review sentences and 11,754 labeled review sentences from Amazon. Experimental results show the efficacy of the proposed framework and its superiority over baselines.

The performance of face recognition has been improved a lot owing to deep Convolutional Neural Network (CNN) recently. Because of the semantic structure of face images, local part as well as global shape is informative for learning robust deep face feature representation. In order to simultaneously exploit global and local information, existing deep learning methods for face recognition tend to train multiple CNN models and combine different features based on various local image patches, which requires multiple forwarding operations for each testing image and introduces much more computation as well as running time. In this paper, we aim at improving face recognition in only one forwarding operation by simultaneously exploiting global and local information in one model. To address this problem, we propose a unified end-to-end framework, named as Split-Net, which splits selective intermediate feature maps into several branches instead of cropping on original images. Experimental results demonstrate that our approach can effectively improve the accuracy of face recognition with less computation increased. Specifically, we increase the accuracy by one percent on LFW under standard protocol and reduce the error by 50% under BLUFR protocol. The performance of Split-Net matches state-of-the-arts with smaller training set and less computation finally.

Neural Machine Translation (NMT) has become a popular technology in recent years, and the encoder–decoder framework is the mainstream among all the methods. It is obvious that the quality of the semantic representations from encoding is very crucial and can significantly affect the performance of the model. However, existing unidirectional source-to-target architectures may hardly produce a language-independent representation of the text because they rely heavily on the specific relations of the given language pairs. To alleviate this problem, in this paper, we propose a novel Bi-Decoder Augmented Network (BiDAN) for the neural machine translation task. Besides the original decoder which generates the target language sequence, we add an auxiliary decoder to generate back the source language sequence at the training time. Since each decoder transforms the representations of the input text into its corresponding language, jointly training with two target ends can make the shared encoder has the potential to produce a language-independent semantic space. We conduct extensive experiments on several NMT benchmark datasets and the results demonstrate the effectiveness of our proposed approach.