It was un satisfactory to use bridging material to repair nerve defect longer than 1.0cm. This experiment used autogenous vein to bridge rabbit tibia nerve with 4.0cm defect. The nerve regeneration did not occur two months after the operation. But when using autogenous vein bridging implanted with Schwann cell homogenate, the electrophysiology, histology, transmission electron microscopy, etc. indicated that the nerve regeneration did occur. This result showed that the length of reparation of nerve defect using non-nerve graft might be increased.

Objective: To treat the loss of part of the forearm with a multi-dimension-freedom electronic artificial hand, which is controlled by a reconstructed finger transplanted from the second toe to the forearm stump. Methods: The female patient was 19 years old, whose right hand and wrist were crushed into pieces by machine at work and her forearm was amputated at the level of 8cm proximal to the wrist. The second toe of her left foot was transplanted to reconstruct the digit onto the stump of her forearm. Two months after the transplantation, the patient was transferred to the rehabilitation center for further rehabilitation training, which consisted of: training for adaptation to weight bearing, testing and training of sensibility to weight. testing and training for stability of the hand, and testing and training for the controlling function of the reconstructed digit. Results: The transplanted toe survived well. After rehabilitation the reconstructed digit functioned well. In testing the performance under control mandate, the accuracy rate of the electronic artificial hand was 100%. Conclusions: A 100% accuracy rate of the electronic artificial hand can be achieved by transplantation of the toe onto the stump of the forearm. It provides a useful pathway and an example for improvement of control accuracy of a multiple-freedom electronic artificial hand and reduction of false action.

目的 将二足趾移植于前臂残端再造手指，利用再造手指控制多自由度电子假手治疗前臂部分缺失。方法 患者女性，19岁，右手及腕部在工作中不慎被机器碾碎，于腕上8cm行前臂截肢。取患者左足第二趾移植于前臂残端再造手指。移植术后二月，患者转入康复中心接受进一步康复训练。包括：①调整承重训练；②重量敏感性测试与训练；③手的稳定度测试与训练；④再造手指的控制能力测试与训练。结果 移植足趾存活良好。经过康复训练再造手指功能良好。指令控制测试中电子假手的准确度为100%。再造手指不仅能够准确地控制单自由度电子假手完成手指伸屈，而且能够精确地操纵三自由度电子假手完成假手手指的屈伸，以及腕关节的屈曲、背伸、旋前、旋后，有助于自理日常生活。结论 通过移植足趾于前臂残端，可以使电子假手达到100%的准确度。作者的报告为提高多自由度电子假手的控制准确度减少误动作提供了有用的途径和范例。

目的：比较游离腓骨或吻合血管腓骨移植治疗切除四肢侵袭性骨肿瘤或恶性骨肿瘤后引起的长段骨缺损的临床疗效。方法：对18例吻合血管移植及4例游离腓骨移植术的病例术后，采用ECT、彩色多普勒血管超声检查、X线照片检查及随访，时间为术后2～12年，移植骨最长达26cm。结果：侵袭性骨肿瘤和恶性骨肿瘤18例，肿瘤切除后用吻合血管腓骨移植重建缺损，15例桡骨远端骨巨细胞瘤患者作游离腓骨移植重建缺损，结果前者愈合良好，移植骨片与受骨接合牢固，游离腓骨移植则愈合较差。结论：吻合血管腓骨移植可一期重建因骨肿瘤或骨恶性肿瘤广泛切除后造成的6cm以上的骨缺损，其优越性远远超过游离腓骨移植。

目的 设计并构建一种新型的神经引导导管。方法 将兔雪旺细胞种到用成粘蛋白多孔医用组织引导的再生胶原膜支架培养2周后，用倒置显微镜、扫描电镜观察雪旺细胞吸附、生长迁移情况；以雪旺细胞胶原膜管的形式植入体内，观察它诱导神经再生的能力。结果 成年兔雪旺细胞在医用组织引导再生胶原膜上生长良好，并均匀分布于支架表面，且基质分泌旺盛。体内模型发现神经已通过移植物长入远端，胶原膜已吸收。结论 雪旺细胞可以在多聚医用组织引导再生胶原膜上得到扩增，种有雪旺细胞的医用组织引导再生胶原膜导管可以形成一个诱导神经轴突再生的微环境，形成的三维立体结构具有人工神经的基本特性，为组织工程方法修复长段神经缺损提供了研究基础。