本文将33例脑膜瘤的ER、PR墁I定结果结合临床、病理资料作了分析。发现PR含量与病人年龄、性别、月经状况、肿瘤太小以及有无CT脑水肿无关。术前应用糖皮质激素组其PR含量明显低于束应用组。上皮型肿瘤的PR含量高于纤维型。PR含量高的肿瘤其均匀型核的出现率较高。提示PR大概能激活染色质部分。

本文分析了147列出血性脑血管病，其中自发性脑出血80例，颅内动脉瘤21例，颅内动青脉畸形32例，自发性蛛网膜下腔出血14例。病人术前间状况、有无脑病及血肿大小对判断高血压性脑出血病人的预后有显著作用。并对与颅内动脉瘤及动静脉畸形手术有关的问题作了讨论。

目的：探讨一种切除中颅凹-颞下凹沟通肿瘤的颅-面联合入路。方法：采用经额颞颧下颌联合手术入路切除肿瘤。结果：显微镜下全切肿瘤的患者经远期随访无神经系统症状及体征。结论：该入路暴露充分，对脑组织牵拉小，能在颈部控制颈内、外动脉，尽早辨认并保护面神经，对切除中颅凹-颞下凹沟通肿瘤十分有利。

In this retrospective study, the results of surgery were examined in 25 patients, 65 years of age or older, suffcring from malignant tumour growth along the cervical spine. The group consisted of 17 men and 8 women. The mean age was 73 years, ranging from 66go 88 years. The pathology identified was medtastasis in 23 patients, and plasmocytoma in two. The tumour localization involved a single segment of the cervical spine in 12 patients, two segments in 8 pa-tients. three scgments in 4 patients, and four segments in one patient. Pre-operatively, 8 patients (32%) suffered solely from severe pain. 6 patients (24%) showed severe pain and radicular nerve compres-tion. 5 patients (20%) had incomplete parta or tetraparesis but were able to walk, and again 6 paticnts (24%) had incomplete para of tetraparesis, and were unable to wald. A multitude of accompanying systemic diseases was present in the majority of patients. Evaluation of the pcri-operative risk profile was parformed using the American Socicty of Anaesthesiology (ASA) Grading of Physical Status Score. Operation consisted of microsurgical tumour removal, usually in-corporationg a single or multi-level vertebrectomy, with radical epi-dural decompression, and grafting with bone cement followed by an ippropriate osteosynthesis. Of the whole cohort of patients treated, four patients were till alive at the time of the last follow-up evaluation. 21 patients did. Four patients died within seven days after surgery. The remaining 17 patients died during the follow-up period. All of these patients died from systemic spread of their primary cancer. The results of mrgery in terms of postoperative neurological outcome were as Fol-lows: 11 patients or 44% were improved by surgery. 7 patients (28%) were unchanged, three patients (12%) became worse, and four pa-tents (16%) died. With regard to functional outcome, 73% of the patients with severe pre-operative neurological deficits showed sig-inficant postoperative amelioration of symptoms. 19 patients became imbulatory until the final sage of their disease. It is concluded, that according to the results of this limited study, general nihilistic or purely conservative approach for the treatment of elderly patients suffering from secondary malignancy of the cer-vical spine is not justified. With proper patient sclection, aggressive mrgery leads to significant amelioration of pre-operatively existing neurological deficits and long-term ambulation in a considerable percentage of the patients.

本文对33例脑膜瘤的ER、PR作了分析。脑膜瘤性激素受体的阳性率：ER。O,ERn为6.1%，PRc为12.1%，PRc为63.3%。多数肿瘤中测不到ER，且测到者台量亦极低。PR含量明显高于ER，认为脑膜瘤以PR占优势。PR与ER间无相关系，且ERc（一）、PRc（+）者明显多于ERc（+），PRc（+）者，提示脑膜瘤的PR可能是一个不依赖于ER调节的独立系统。本资料为脑膜瘤的激素治疗可能性提了理论依据。