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2006年06月26日

【期刊论文】Methylation of p16 CpG Islands Associated with Malignant Transformation of Gastric Dysplasia in a Population-Based Study

邓大君, Yu Sun, Dajun Deng, Wei-Cheng You, Hua Bai, Lian Zhang, Jing Zhou, Lin Shen, Jun-Ling Ma, Yu-Quan Xie, and Ji-You Li

Vol. 10, 5087-5093, August 1, 2004,-0001,():

-1年11月30日

摘要

Purpose: Inactivation of p16 by aberrant methylation of CpG islands is a frequent event in carcinomas and precancerouslesions of various organs, including the stomach. Theaim of this study is to investigate the relationship betweenp16 methylation and mali

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2006年06月26日

【期刊论文】Methylation of CpG islands of p16 associated with progression of primary gastric carcinomas

邓大君, Daya Luo*, Baozhen Zhang*, Lingbo Lv, Shengyan Xiang, Yahang Liu, Jiafu Ji and Dajun Deng

,-0001,():

-1年11月30日

摘要

Inactivation of p16 by methylation of CpG islands is a frequent early event in gastric carcinogenesis. Thepositive relationship between p16 methylation and the clinical characteristics of gastric carcinomas (GC) hasnot been reported to date. In the presen

CpG Islands, DHPLC, gastric carcinoma, methylation, p16, quantification

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2006年06月26日

【期刊论文】Formation of A2143G Mutation of 23S rRNA in Progression of Clarithromycin Resistance in Helicobacter pylori 26695

邓大君, JING SHEN, , JIAN-ZHONG ZHANG, YANG KE, and DAJUN DENG

MICROBIAL DRUG RESISTANCE Volume 11, Number 2, 2005,-0001,():

-1年11月30日

摘要

The aim of this work was to investigate the link between 23S rRNA mutation and clarithromycin (CLR)-resistantHelicobacter pylori (H. pylori). CLR-resistant (CLRr) H. pylori strains were selected from the parentstrain, H. pylori 26695, using medium contain

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2006年06月26日

【期刊论文】Hypermethylation of metallothionein-3 CpG island in gastric carcinoma

邓大君, Dajun Deng, , Wa'el El-Rifai, Jiafu Ji, Budong Zhu, Paul Trampont, Jiyou Li, Michael F.Smith and Steven M.Powell

Carcinogenesis vol.24 no.1 pp. 25-29, 2003,-0001,():

-1年11月30日

摘要

The expression of metallothionein (MT)-3 is often markedly reduced in gastric carcinoma (GC). The molecular mechanism of this MT-3 downregulation is unknown. Transcriptional silencing of MT-3 by methylation of CpG island was investigated by nucleotide seq

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2006年06月26日

【期刊论文】Formation of N-(Nitrosomethyl)urea in Stomachs of Experimental Pigs and Human Volunteers Given Fish Sauce in Vivo

邓大君, Dajun Deng* and Huijun Xin

J. Agric. Food Chem. 2000, 48, 2495-2498,-0001,():

-1年11月30日

摘要

N-(Nitrosomethyl)urea (NMU) was characterized in carcinogenic nitrosated fish sauce recently (Denget al. J. Agric. Food Chem. 1998, 46, 202-205; Biomed. Environ. Sci. 1999, 12, 54-61). To studythe possibility of intragastric synthesis of NMU, experimental

Nitrosomethylurea, fish products, nitrosation, pig, human, gastric juice, stomach cancer, nitrosamide, nitroso compounds, nitrite, HPLC

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    北京大学,北京

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