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2006年06月26日

【期刊论文】Simultaneous detection of CpG methylation and single nucleotide polymorphism by denaturing high performance liquid chromatography

邓大君, Dajun Deng, , *, Guoren Deng, Michael F. Smith, Jing Zhou, Huijun Xin, Steven M. Powell and Youyong Lu

Nucleic Acids Research, 2002, Vol. 30, No.3 e13,-0001,():

-1年11月30日

摘要

We report here a novel method to simultaneouslydetect CpG methylation and single nucleotide polymorphisms(SNPs) using denaturing high performanceliquid chromatography (DHPLC). PCR products ofbisulfite-modified CpG islands were separated usingDHPLC. BstUI

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2006年06月26日

【期刊论文】Characterization of N-(Nitrosomethyl) urea in Nitrosated Fermented Fish Products

邓大君, Dajun Deng, *, Tong Li, Hong Ma, Ruming Wang, Liankun Gu, and Jing Zhou

J. Agric. Food Chem., Vol. 46, No.1, 1998,-0001,():

-1年11月30日

摘要

To characterize chemical carcinogens in acidic-nitrosated fish sauce sample, N-nitrosamides in thesample were separated by two kinds of reversed-phase HPLC columns, and with detection byphotolysis-pyrolysis-thermal energy analyzer. A strong chromatographi

Nitrosomethylurea, fish products, nitrosation, human, gastric juice, stomach cancer, nitrosamide, nitroso compounds, nitrite

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2006年06月26日

【期刊论文】progress of gastric cancer etiology: N-nitrosamides

邓大君, Da Jun Deng

World J Gastroentero, 2000; 6 (4): 613-618,-0001,():

-1年11月30日

摘要

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2006年06月26日

【期刊论文】p16 hypermethylation during gastric carcinogenesis of Wistar rats by N-methyl-N-nitro-N-nitrosoguanidine

邓大君, Hua Bai, Liankun Gu, Jing Zhou, Dajun Deng*

Mutation Research 535 (2003) 73-78,-0001,():

-1年11月30日

摘要

Inactivation of the tumor suppressor gene, p16 by CpG hypermethylation is a common event in various tumors includinggastric carcinoma. The aim of this study is to investigate if p16 hypermethylation is an early and frequent event in gastric carcinogenesis

CpG island, p16, Methylation, Wistar rat, Gastric carcinogenesis, Carcinogen, N-Nitroso compound

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2006年06月26日

【期刊论文】Formation of A2143G Mutation of 23S rRNA in Progression of Clarithromycin Resistance in Helicobacter pylori 26695

邓大君, JING SHEN, , JIAN-ZHONG ZHANG, YANG KE, and DAJUN DENG

MICROBIAL DRUG RESISTANCE Volume 11, Number 2, 2005,-0001,():

-1年11月30日

摘要

The aim of this work was to investigate the link between 23S rRNA mutation and clarithromycin (CLR)-resistantHelicobacter pylori (H. pylori). CLR-resistant (CLRr) H. pylori strains were selected from the parentstrain, H. pylori 26695, using medium contain

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    北京大学,北京

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