Research Progress on Functions of Plant RING-type E3 Ubiquitin Ligases

• 1、 Longping Agricultural College, Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan Provincial Hybrid Rape Engineering Technology Research Center, Hunan University, Changsha 410082, China

Abstract：The ubiquitin-proteasome system is an essential post-translational modification system in eukaryotes. As core components of the ubiquitination pathway, E3 ubiquitin ligases recognize target substrates and determine the specificity of ubiquitination. RING-type E3 ligases feature a conserved RING domain and represent the largest and most functionally diverse class of E3 ligases in plants. Accumulating evidence indicates that RING-type E3 ligases mediate the ubiquitination and degradation of specific substrates, thereby widely regulating multiple plant life processes, including seed germination, flowering, organ development and senescence. They also participate in plant responses to abiotic stresses such as drought, extreme temperature and salinity, and in defense against pathogen-induced biotic stresses, as well as modulating the signal transduction of various plant hormones. This article systematically reviews the research progress of plant RING-type E3 ligases in growth and development, stress responses, and hormone signaling, and discusses future research directions, aiming to provide a theoretical reference for related studies.

Keywords： Molecular Biology RING-type E3 ubiquitin ligases Abiotic stress Biotic stress Plant growth and development