Objective: To find effective therapeutic approach f。r treating true idi。pathic precocious pubertv suitable to OU F national condilion and different from gonadotrophin releasing hormone aIlalogue Metbs: Onc hundred and SIX gifts with idiopathic precocious puberty were divided into 3 groups The 51 girls in the TCM WM group were treated with Chinese herbal medicine combined with megestr. l acctatc(MA), 35 girls in the MA group treated with megestrol acetate alone, and 20 girls were taken 8s control group and given n. trea LIncnt at all Luteinizing hormone releasing hormone (LHRH) sticau]ating test were performed before and after treat ment, and the size ol the uterus and ovary, linear growth rate, X-ray bone age measurement and final heighy prediction were also observed simultaneously Results：Aher t reared with TCM WM for 27 years in average, the luteinizing hormone (LH) peak value of LHRH stimulating test was reduced front 48.5±5.2 IU/L FO 12 2±1.3IU/L, size of uterus and Ovary decreased, secondary sexual characteristics rezressed, the bone age difterence/chronoIogical age difference value (ABA/ACA) reduced from 1.35±0.09 to 0.65+0.05 and predictive final height increased front 153.3±0.5cm to 158.5+0.6cm. Conclusion: TCM-WM therapy could not only modulate the function of hypothalamic-pltuitary-ovarian axis and the development of internal, genhalia. but also cluld decelerate skeletal growth, delay skeletal maturation, and thereby prevent premature epiphyseal fusion and increase the final height of patiehts.