A silicone-containing epoxide named as EPSIB was prepared for silk crease-resist finishing. The major influence parameters for the synthesis of EPSIB were discussed. These treatments are shown to improve significantly both dry and wet resiliencies of silk with a good laundering durability. The shrinkage of finished silk by EPSIB was also improved. Other properties such as breaking strength, abrasion resistance and moisture regain remain almost constant. The results obtained in this study indicated that EPSIB may be suitable for commercial exploitation for silk finishing.