Accumulation of protein and starch in grain is a key procss determining grain yield and quality in wheat. Under drought or waterlogging, endogenous plant hormone levels will change and may have and impact on the yield and quality of wheat. In a greenhouse experimnet, four winter wheat (Triticum aestivum L.) varieties differing in grain protein conternt. Heimai 76. Wanmai 38. Yangmai 10 and Yangmai 9, were subjected to drought (SRWC=45～50%, DR). waterlogging (WL) and moderate water supply (SRWC=75～80%, CK), beginning form 4 days post-anthesis (DPA) to maturity. On the 10 (grain enlargemet stage) and 20 (grain filling stage) DPA. endogenous in sink and source organs of wheat plants by enxymc linked immunosorbent assay (ELISA). The patterns of hormonal changes were similar in four varieties. The ABA levels were much higher under DR and WL than under CK. Compared with CK, GA1+3 levels in whole-plant under DR and WL changed a little at 10 DPA, but markedly dectrease under DR and WL at 20 DPA. Changes of enodgenous IAA level under DR and WL exhibited a complicated pattern, depending on organs and growth stages. Particularly at the 20 DPA, the mean levels of IAA in roots. leaves and grains decreased significantly under DR and WL. In comparison with CK. ZR levels in all organs significantly decreased under DR and WL at both stages. The correlation analyses between yiclds and contents of starch and protein in grains and levels and rations of four hormones in source and sink organs indiated that the changes in yield and content of grain starch and protein under DR and WL were associated with the reduced IAa, ZR and GA, levels and elevated ABA level in plants, expecially in grains. It was proposed that the changed levels of endongenous hormones under post-anthesis DR and WL might indirectly affect protein and starch accumulation in grains by influencing the regulatory enzyines and rpocesses.