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Novel Sesquiterpene Esters with Alkaloid and Monoterpene and Related Compounds from Tripterygium Hypoglaucum:A New Class of Potent Anti-HIV Agents

段宏泉Hongquan Duan a Yoshihisa Takaishti a* Masahiko Bando b Masaru Kido b Yasuo Imakura c and KuoHsiung Lee d

Tetrahedron Letters 40(1999)2969~2972,-0001,():

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摘要/描述

Two new sesquiterpene polyol esters (triptonine A and B) with alkaloid and monoterpene were isolated from Tripterygium hypoglaucum (Levi.) Hutch. Their structures were elucidated by spectroscopic means and X-ray analysis. Triptonine A (1) and hypoglaunine B3) (4) demonstrated potent anti-HIV activity with EC50 values of 2.54 and 0.13

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