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刘昭前
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期刊论文
Effect of the CYP2C19 oxidation polymorphism on
2001 Blackwell Science Ltd Br J Clin Pharmacol, 52, 96-99，-0001，（）：
Aims The study was designed to investigate whether genetically determined CYP2C19 activity affects the metabolism of fluoxetine in healthy subjects. Methods A single oral dose of fluoxetine (40mg) was administrated successively to 14 healthy young men with high (extensive metabolizers, n=8) and low (poor metabolizers, n=6) CYP2C19 activity. Blood samples were collected for 5
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