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期刊论文

Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels

麻彤辉TONGHUI MA SUJATHA JAYARAMAN KASPER S. WANG YUANLIN SONG BAOXUE YANG JIANG LI J. AUGUSTO BASTIDAS AND A. S. VERKMAN

Am J Physiol Cell Physiol 280: C126–C134, 2001.,-0001,():

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摘要/描述

Ma, Tonghui, Sujatha Jayaraman, Kasper S. Wang, Yuanlin Song, Baoxue Yang, Jiang Li, J. Augusto Bastidas, and A. S. Verkman. Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels. Am J Physiol Cell Physiol 280: C126-C134, 2001.-Immunocytochemistry showed expression of aquaporin-1 (AQP1) water channels at sites involved in dietary fat processing, including intrahepatic cholangiocytes, gallbladder, pancreatic microvascular endothelium, and intestinal lacteals. To determine whether AQP1 has a role in dietary fat digestion and/or absorption, mice were placed on a diet that contained 50% fat. Whereas wild-type mice (3-3.5 wk of age, 10-12g) gained 49

关键词: water transport bile pancreas

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