The present study investigated the effects of shear slip on the deformation of steel-concrete composite beams. The equivalent rigidity of composite beams considering three different loading types was first derived based on equilibrium and curvature compatibility, from which a general formula to account for slip effects was then developed. The predicted results were compared with measurements of six specimens tested in the present study and other available test results for both simply supported and continuous beams. It was found that including slip effects has significantly improved the accuracy of prediction. For typical beams used in practice, shear slip in partial composite beams has a significant contribution to beam deformation. Even for full composite beams, slip effects may result in stiffness reduction up to 17% for short span beams. However, slip effects are ignored in many design specifications that use transformed section method except that American Institute of Steel Construction (AISC) specifications recommend a calculation procedure in the commentary. In the AISC procedure, stress and deflection calculations of partially composite girders are based on effective section modulus and moment of inertia to account for slip, while ignoring slip effects in full composite sections. For full composite sections, the effective section modulus and moment of inertia calculated with the AISC specifications are larger than that of present study, meaning that the specifications are not on the conservative side. For partial composite sections, the AISC predictions are more conservative than the present study.