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期刊论文

A coumarin derivative covalently immobilized on sensing membrane as a fluorescent carrier for nitrofurazone

牛承岗Chen-Xu Jiao Cheng-Gang Niu Li-Xin Chen Guo-Li Shen Ru-Qin Yu

Anal Bioanal Chem (2003) 376: 392-398,-0001,():

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摘要/描述

A coumarin derivative 4-methyl-8-methylacrylamide-2H, 5H-pyrano [3, 2-C] benzpyran 2, 5-dione (MMPBD) has been synthesized as a fluorescent carrier for preparing an optical chemical sensor. The carrier is immobilized on a quartz glass plate surface treated with a silanizing agent to prevent the leakage of the dye. This MMPBD sensor can be utilized for a nitrofurazone (NF) assay based on fluorescence quenching. The sensor shows good repeatability, a long lifetime and a fast response of less then 50 s. NF can be determined in the range between 1.0×10-6-1.0×10-3mol L-1 with a detection limit of 8.0×10-7 mol L-1 at pH 7.0.

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