Mesoporous titania nanoparticles with high specific surface area and thermal stable anatasewallwas synthesized from surfactant laurylamine hydrochloride (LAHC) and inorganic precursor Ti(SO4)2. The as-synthesized and calcined materials were characterized by X-ray diffraction, nitrogen adsorption-desorption, transmission electron micrographs, Fourier transform infrared spectroscopy and thermogravimetric analysis. The obtained mesoporous TiO2 nanoparticles have mean diameter of 25.5 nm. The specific surface area of the mesoporous nanosized TiO2 calcined at 400℃ exceeded 189m2 g−1, and that of the samples after calcinations at 500℃ still have 151m2 g−1. The obtained anatase mesoporous TiO2 nanoparticles show relative high thermal stability.