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期刊论文
Endomorphin and m-opioid receptors in mouse brain mediate the analgesic effect induced by 2Hz but not 100Hz electroacupuncture stimulation
Neuroscience Letters 294(2000)159-162，-0001，（）：
This work was designed to examine whether brain endomorphins (EM1 and EM2), the endogenous m-opioid ligands, are involved in electroacupuncture (EA)-induced analgesia in the mice. C57BL/6J mice were given EA for 30min and the effect of EA-induced analgesia was assessed by radiant heat tail-ick latency (TFL). Intracerebroventricular (i.c.v.) injection of m-opioid receptor antagonist D-Phe-Cys-Tyr-D-Tyr-Orn-Thr-Pen-Thr-NH2 (CTOP), or antiserum against EM1 or EM2 was performed to see whether EA analgesia could be blocked. The results showed that: (1) i.c.v. injection of CTOP at 25
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