High-spin states in 180Ir have been investigated by means of in-beam g-ray spectroscopy techniques with the 154Sm (31P,5nγ)180Ir reaction. Excitation functions, x-γ and γ-γ-t coincidences, DCO (directional correlation of grays deexciting oriented states) ratios, and intraband B(M1)/B(E2) ratios were measured. Five rotational bands have been identified and their configurations are proposed on the basis of B(M1)/B(E2) ratios and by comparing the band properties with known bands in neighboring odd-mass and even-mass nuclei. The neutron AB crossing is observed at hωc=0.26(1) MeV for the π1/2-[541]⊗v1/2-[521] and π1/2-[541]⊗v5/2-[512] bands, respectively. Staggering of levels as a function of the number of neutron pairs is revealed in the π1/2-[541]⊗v1/2-[521] doubly decoupled bands of 178-186Ir. The gradual alignment gains at low rotational frequencies are observed in the two strongly coupled bands. Band crossings and alignments in 180Ir are discussed with reference to the total Routhian surface and cranked shell model calculations performed for the neighboring odd-mass nuclei.