Laser direct manufacturing (LDM) has been intensively developed in recent years to directly and flexibly manufacture metallic components with full metal density, functions and properties, especially for some specific materials or geometry. This paper presents a projectwork on laser direct manufacturing a novel designed collimation component for an out-space hard X-ray modulation telescope. The research work contained the characteristics of overlap multi-pass laser cladding of tungsten or tungsten nickel alloys, microstructure analyses, technique stability of laser direct manufacturing, and the final direct manufacturing of tungsten nickel collimation component. The results proved that laser direct manufacturing could be well used to manufacture specific material and geometry component of good quality, which are very difficult or even impossible by conventional manufacturing methods.