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周先礼

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期刊论文

Hemsleyatine, a Novel C19-Diterpenoid Alkaloid with 8-Amino Group from Aconitum hemsleyanum1)

周先礼Xian-Li ZHOUa Qiao-Hong CHENb Dong-Lin CHENb and Feng-Peng WANG*b

Chem. Pharm. Bull. 51(5)592-594 (2003),-0001,():

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摘要/描述

The new compound hemsleyatine (1) was isolated along with four known C19-diterpenoid alkaloids: indaconitine (4), yunaconitine (5), chasmanine (6), and talatisamine (7) from the roots of Aconitum hemsleyanum PRITZ. Structures were established by spectral analysis, including tow dimeusional (2D) NMR spectroscopy and a chemical method. Hemsleyatine (1) is the first C19-diterpenoid alkaloid bearing the 8-amino group. In addition, the assignments of some 13C signals for pseudaconine (3) were revised by comparison with those of hemsleyatine (1).

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