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孙作东

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期刊论文

Enlightening Point of View Based on Potassium Channel “Origami Windmill” Model

Zuodong Sun

Journal of US-China Medical Science,2020,17(4):109-131 | 2020年08月20日 | 10.17265 / 1548-6648 / 2020.04.001

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摘要/描述

Applying the K+ channel origami windmill model principle, the whole process of action potential generation of nerve fiber cells and cardiomyocytes is explained reasonably. Its core view is: cell action potential decline phase, dominated by influx of potassium ions. This is contrary to the core idea of the traditional theory—ionic theory. According to ionic theory, cell action potential decline phase, dominated by outflow of K+ ions. In the face of such two opposing views, the author traces back to the source, combing and commenting on the basic theoretical research on the production mechanism of cell bioelectricity generation and the results of classical basic experiments. And a series of enlightening viewpoints are produced:1. Ionic theory has its preexistence deficiency; 2. There are principle defects in GHK equation and H-H equation; 3. Ion channels may “same direction sharing”; 4. Sodium-potassium pumps, calcium pumps and so on May not exist. The thesis's Point is falsifiable. If “cell action potential decline stage, dominated by outflow of K+ ions” can be proved, all the points in this paper will not be true. On the contrary, the series of enlightening views in this paper will inevitably lead to a revolution in the field of life science. The viewpoint of this paper is not only closely related to the causes of human major diseases, treatment principles and methods, but also may have a profound impact on the future research direction of life science researchers.

【免责声明】以下全部内容由[孙作东]上传于[2020年08月20日 14时38分16秒],版权归原创者所有。本文仅代表作者本人观点,与本网站无关。本网站对文中陈述、观点判断保持中立,不对所包含内容的准确性、可靠性或完整性提供任何明示或暗示的保证。请读者仅作参考,并请自行承担全部责任。

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