利用桥接物修复1.0cm以上神经缺损，效果不理想。本实验采用自体静脉桥接家兔4.0cm长胫神经缺损，术后2个月未发生神经再生现象。而利用自体静脉内种植雪旺氏细胞匀浆，桥接家兔4.0cm长胫神经缺损，术后电生理、组织学、透射电镜等项检测指标都能观察到神经再生现象。雪旺氏细胞匀浆在静脉桥接物的这一作用，增加了非神经移植物修复神经缺损的长度。

应用带血管腓骨治疗上肢侵袭性良性骨肿瘤和恶性骨肿瘤10例，不带血管腓骨治疗桡骨远端骨巨细胞瘤13例，总共23例。随访时间2～12年，随访中使用ECT（单光子照射扫描照相），彩色多普勒血管超声检查，以及X线片检查。结果显示带血管腓骨10例移植骨片生长良好，移植骨片与受骨愈合牢固；不带血管腓骨移植骨片长度超过6cm时愈合困难。本组带血管腓骨移植骨片最长26cm，最短9cm，这种手术最大的进步是病变组织可彻底切除，切除后可一期重建缺损组织。另一个优点是移植后的骨片周径可有增粗。

目的：比较游离腓骨或吻合血管腓骨移植治疗切除四肢侵袭性骨肿瘤或恶性骨肿瘤后引起的长段骨缺损的临床疗效。方法：对18例吻合血管移植及4例游离腓骨移植术的病例术后，采用ECT、彩色多普勒血管超声检查、X线照片检查及随访，时间为术后2～12年，移植骨最长达26cm。结果：侵袭性骨肿瘤和恶性骨肿瘤18例，肿瘤切除后用吻合血管腓骨移植重建缺损，15例桡骨远端骨巨细胞瘤患者作游离腓骨移植重建缺损，结果前者愈合良好，移植骨片与受骨接合牢固，游离腓骨移植则愈合较差。结论：吻合血管腓骨移植可一期重建因骨肿瘤或骨恶性肿瘤广泛切除后造成的6cm以上的骨缺损，其优越性远远超过游离腓骨移植。

Objective To compare the effect of vascularized and non-vascularized fibula grafting performed for the reconstruction of bone defects after the resection of bone tumors. Methods Vascularized fibula grafting was performed in 18 patients with malignant or aggressive benign bone tumor of the extremities. Non-vascularized fibula grafting was performed in 15 patients with giant cell tumor of the radius. All the 18 patients were followed up with radiography, single photon emission computed tomography (SPECT), colored Doppler's sonography (CDS) examinations and functional observation for 2 to 14 years. Results Vascularized fibula grafts with bone defects of 9 to 26cm showed good blood supply in emission computerized tomography (ECT) and radiography examinations, and bone union was achieved (Table 1). In non-vascularized fibula grafting cases (Table 2), bone union was not achieved. Cconclusions The advantages of vascularized grafting are the feasibility of one-stage reconstruction of various tissues and the growth of grafted fibula. It is necessary to adopt vascularized fibula grafting to reconstruct large bone defect resulting from the resection of extensive bone tumors, such as giant cell tumor (GCT), fibrous dysplasia of bone and malignant bone tumors.