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2005年05月31日
【期刊论文】Synthesis and Cytotoxicity of 2-Amido Docetaxel Analogues
方唯硕， Wei-Shuo Fang， * Ying Liu， Hong-Yan Liu， Shao-Feng Xu， Liang Wang and Qi-Cheng Fang
Bioorganic & Medicinal Chemistry Letters 12(2002)1543-1546，-0001，（）：
-1年11月30日
—Various 2-amido docetaxel analogues were prepared and evaluated for their cytotoxicities. Among them, m-methoxy and m-chlorobenzoylamido analogues were most active but not superior to docetaxel and paclitaxel, and d-seco analogues inactive. Change of 2-benzoate to 2-benzamide may not improve their activities to drug-resistant cell lines.
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