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【期刊论文】Ribosome–Lamella Complex Precursors in Acute Monocytic Leukemia: A Study of 6 Cases
茹永新
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-1年11月30日
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【期刊论文】Invasion of Erythroblasts by Pasmodium vivax: A New Mechanism Contributing to Malarial Anemia
茹永新, Yong-Xin Ru, MD, Bing-Yu Mao, Feng-kui Zhang, Tian-xiang Pang, Shi-xuan Zhao, BSc, and Jin-Hua Liu
Ultrastructural Pathology, 33: 236-242, 2009,-0001,():
-1年11月30日
Severe malarial anemia causes considerable mortality and morbidity in endemic areas. Possible mechanisms underlying the anemia include lysis of parasitized and nonparasitized red cells as well as parasite product-mediated effects on erythropoiesis. The latter include suppression of erythropoiesis, dyserythropoiesis, and ineffective erythropoiesis. Present transmission electron microscope data in two cases of Pasmodium vivax malaria show a hitherto undescribed mechanism contributing to malarial anemia, namely, infection of erythroblasts by parasites and their subsequent degradation. No parasites were detected in the peripheral blood but parasites were found in the bone marrow. These findings emphasise the value of bone marrow examination in the diagnosis and eradication of malaria.
bone marrow,, erythroblasts,, malarial anemia,, mechanism
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【期刊论文】Congenital dyserythropoietic anemia in a Chinese family with a mutation of the CDAN1-gene
茹永新
,-0001,():
-1年11月30日
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21浏览
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