This study investigated the therapeutic e¡ect of neural stem cells transplantedvia the carotid artery atdi¡erent times after intracerebral hemorrhage. A great number of 5-bromo-2-deoxyuridinepositive cells were observed surviving and distributed evenly in the perihematoma areas. Phenotypes of grafted cells depended upon time of transplantation, and the later the cells were transplanted, the larger the percentage of cells that di¡erentiated into neurons. Animals treated at 7 and14 days after injury exhibited the most signi¢cant improvements in behavioral tests. Therefore, intracarotid injection allows e⁄cient delivery of cells to the injured hemisphere, especially during the period 7^14 days after injury, and may potentially be applicable in humans. NeuroReport 18:1019-1023 2007 Lippincott Williams & Wilkins.

Background: Traumatic subdural hydroma (TSH) is a common complication of head injuries. The aim of this study was to examine the clinical characteristics and classification of TSH. Methods: One hundred and ninety-two patients with TSH were treated in Qilu hospital during a 13-year period (1989–2001). We reviewed each patient’s clinical records and radiological findings. Results: Based on clinical features and dynamic observation of CT scanning, TSHs were classified into four types: resolution, steadiness, development and evolution. The resolution type often occurred in the prime of life, and the patients had normal intracranial pressure and good prognoses after conservative treatment. The elderly made up the majority of the steadiness type. Their main clinical manifestations included headaches, dizziness, nausea, vomiting, abnormalmentality, etc. Generally, no positive nervous systemic sign related to TSH was observed. The prognoses of the steadiness type treated by conservative therapy were also satisfactory. The development type was common in babies and children and mainly manifested as progressively increasing intracranial pressure, mild hemiplegia, aphasia and abnormal mentality. The patients with development type often needed surgical treatment where there was an associated risk of dying from accompanying cerebral parenchymal damage or postoperative complications once in a while. The evolution type with chronic subdural haematoma occurred between 22 and 100 days after TSH and in the cases of small hydromas treated conservatively, with mild accompanying cerebral damage, characterised by the polarised age, and chronic increased intracranial pressure, there was always a good prognosis after surgery. Conclusions: The mechanism, clinical characteristics, treatment methods and prognoses varied with the different types of TSH.

本文综合山东省11家医院经手术及病理证实的第三脑室胶样囊肿14例。占同期颅内肿瘤的0.14%。8例行脑室造影，6例CT扫描。经额入路手术切除13例，定向活检囊液抽吸排空1例，其中脑脊液分流术3例。治愈6例，好转7例，死亡1例。着重对其诊断与治疗进行了讨论。

目的探讨外伤性硬膜下积液演变为慢性硬膜下血肿的几率、机理和临床特点。方法回顾性分析%!例外伤性硬膜下积液演变为慢性硬膜下血肿患者的临床资料及有关文献。结果本组16.7%的外伤性硬膜下积液病例演变为慢性硬膜下血肿；积液演变为血肿的时间为伤后22～100D；经钻颅血肿引流均治愈。结论外伤性硬膜下积液是慢性硬膜下血肿的来源之一。发病年龄两极化，常发生在积液量少、保守治疗的慢性型病例中。致病方式常为减速性损伤及合并的颅 脑损伤很轻微是外伤性硬膜下积液演变为慢性硬膜下血肿患者的临床特点。