目的：分析人工晶体术后继发青光眼的临床特征。方法：分析36例36只眼人工晶体术后继发青光眼患者视力、眼压、房角、人工晶体情况、青光眼类型、超声生物显微镜（UBM）检查及治疗情况。结果：36眼视力为无光感～0.8，平均眼压为42.8±15.1mmHgo26只眼（72.2%）房角关闭，9只眼（25%）房角开放。11只眼（30.5%）人工晶体偏位（6只眼人工晶体夹持）；人工晶体拌位置异常者7例（19.4%）.继发闭角型青光眼26只眼（72.2%），开角型青光眼9只眼（25.0%）。15只眼行UBM检查，图象显示4只眼虹膜膨隆房角关闭，5只眼虹膜平坦房角关闭，3只眼为宽角;2只眼睫状体水肿.9只眼人工晶体位置正常，6只眼人工晶体和域拌位置异常，2只眼晶体皮质残留。33只眼施手术治疗，3只眼单纯药物治疗，治疗后眼压为12.0±4.6mmHg，治疗后视力低于0.3者26只眼（72.2%）。结论：人工晶体术后继发青光眼原因复杂，临床表现多样化，治疗棘手，视功能恢复不良。UBM对人工晶体术后继发青光眼诊断、分析及处理有较好的辅助作用。

Objective To identify the characteristics of and evaluate surgical impact on idiopathic macular hole (IMH) by using an optical coherence tomography (OCT) scanner. Methods Sixty-five cases (70 eyes) experiencing IMH were examined using OCT, then graded by their clinical characteristics. Nineteen cases (19 eyes) were scanned and measured using OCT before and after surgery. Results Of the 70 eyes, the number of stage I-IV macular holes were 11, 12, 36 and 11, respectively. For stage I holes, the OCT images revealed flattened or nonexistent fovea and minimally reflective space within or beneath the neurosensory retina; stage Ⅱ holes appeared to be full-sized with attached operculum and surrounding edema; stage Ⅲ holes were also full-sized with surrounding edema; finally, stage IV holes were full-sized and completely separated the posterior hyaloid membrane from the retina. Through quantitative measurements, OCT determined that the values for mean hole diameter, mean halo diameter and mean thickness of the hole's edge were reduced from 570.95±265.59 to 337.05±335.95μm, 1043.53±278.8 to 695.00±483.00μm and 389.78±60.58 to 298.78±109.80μm, respectively in 19 IMH cases after surgery. In 17 eyes, the holes or halos eventually closed or were reduced in size, or the edges of the holes thinned out. The anatomic successful rate of the surgery was 89%. Conclusion OCT can exhibit the characteristics of IMH and measure the diameter of holes quantitatively. This method can also judge the surgical impacts of IMH objectively, accurately and effectively.

Objectives To investigate image characteristics and thickness of the retinal nerve fiber la yer (RNFL) in normal and glaucomatous eyes using optical coherence tomography (OCT), and analyze the relationship between RNFL thickness and visual field index. Methods Eighty-three normal persons (150 eyes) and 83 patients with primary open angle glaucoma (POAG, 149 eyes) underwent OCT examinations with 3.4mm diameter circ le scan to calculate the RNFL thickness. Statistical analysis was used to compa re differences in RNFL thickness in quadrants and means between the normal and glaucomatous groups and the different stages of POAG. Linear correlation and reg ression analysis were used to show the correlation between RNFL thickness and vi sual field index of 115 eyes in glaucomatous patients. Reproducibility, sensiti vity and specificity of RNFL measurements using OCT were evaluated. Results RNFL thickness measured by OCT in normal subjects was thicker in superior and in ferior, less in temporal, and thinnest in nasal quadrants. The curve showed dou ble peaks. RNFL of glaucomatous patients showed local thinning or defect, diffu se thinning, or both. The mean RNFL thicknesses of the normal group in the temp oral, superior, nasal and infeior quadrants were 90.1±10.8μm, 140.4±10.5μm, 85.2±14.0μm, and 140.4±9.7μm, respectively with a mean of 114.2±6.0μm.The numbers for the glaucomatous group were respectively 56.0±31.0μm, 81.0±36.3μm, 47.1±27.5μm, and 73.4±38.4μm for th e four quadrants, with a mean of 64.6±28.8μm. There was a significant dif ference in RNFL thickness between the normal and glaucomatous groups (P<0.000), and the three stages (early, developing and late) of glaucomatous groups (P<0.000). There was a close negative relationship between RNFL thickness a nd visual field index (r=-0.796, P<0.0001). The sensitivity and speci ficity of RNFL thickness in POAG measured using OCT were 93.3% and 92.0%, res pectively. Conclusions OCT can quantitatively measure RNFL thickness differences between normal persons and glaucomatous patients. RNFL thickness gradually decreases while visual fie ld defect increases with the development of POAG.