已为您找到该学者7条结果 成果回收站
【期刊论文】ENDOTHELIUM-DEPENDENT RELAXATION INDUCED BY HAWTHORN EXTRACT IN RAT MESENTERIC ARTERY
张泽生, Z.Y. Chen, Z.S. Zhang, K.Y. Kwan, M. Zhu, W.K.K. Ho, and Y. Huang
Hawthorn and Vasorelaxation 63 22(1998)1983-1991,-0001,():
-1年11月30日
The extract prepared from hawthorn (Crataegus fruit) was examined for its relaxant effect in rat isolated mesenteric arteries. Hawthorn extract induced concentrationdependent relaxation of the U46619-precontracted artery with an IC50 of 0.22
hawthorn, crataegus fruit, relaxation, endothelium, nitric oxide, artery
-
23浏览
-
0点赞
-
0收藏
-
0分享
-
75下载
-
0
-
引用
【期刊论文】Hawthorn Fruit Is Hypolipidemic in Rabbits Fed a High Cholesterol Diet1
张泽生, Zesheng Zhang, Walter K. K. Ho, Yu Huang, * Anthony E. James, † Lik Wang Lam† and Zhen-Yu Chen
American Society for Nutritional Sciences. (2002) 5-10,-0001,():
-1年11月30日
The present study examined the hypolipidemic activity of hawthorn fruit. New Zealand white rabbits were fed one of three diets, a reference diet with no cholesterol added (NC), a high cholesterol diet (1g/100g, HC) and a HC diet supplemented with 2g/100g hawthorn fruit powder (HC-H). After 12 wk, serum total cholesterol (TC) and triacylglycerols (TG) were 23.4 and 22.2% lower, respectively, in the hawthorn fruit group compared with the HC rabbits (P﹤0.05). Hawthorn supplementation led to 50.6% less cholesterol accumulation in aorta (P﹤0.05) and 23-95% greater excretion of neutral and acidic sterols (P﹤0.05). Supplementation of hawthorn fruit did not affect the activities of hepatic 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG-CoA-R) or cholesterol 7 -hydroxylase (CH) but it suppressed the activity of intestinal acyl CoA:cholesterol acyltransferase (ACAT, P ﹤0.05). The results suggest that the mechanism by which hawthorn fruit decreases serum cholesterol involves, at least in part, the inhibition of cholesterol absorption mediated by down-regulation of intestinal ACAT activity. J. Nutr. 132: 5-10, 2002.
cholesterol, Crataegus pinnatifida, hawthorn fruit, rabbits, triglycerides
-
34浏览
-
0点赞
-
0收藏
-
0分享
-
74下载
-
0
-
引用