2006年10月24日，在安徽省六安市金寨县响洪甸水库附近的矿洞中捕捉到1只腹侧颈部白化的雌性几内亚长翼蝠（Miniop terus magnater: Chiroptera，Vespertilionidae），该只白化个体的体重、头体长、前臂长、胫骨长、后足长、尾长、耳长和耳宽分别为14.4g、50.1mm、48.2mm、20.7mm、9.3mm、51.2mm、10.7mm和8.8mm，均在正常个体数据范围之内。

自由声场刺激条件下，采用单单位胞外微电极记录方法，研究了一种未被研究过的恒频/调频（CF/FM）蝙蝠——菲菊头蝠（Rhinolophus pusillus）的下丘神经元基本声反应特性，其结果发现，在所得的110个下丘神经元中，发放类型包括相位型（54.5%）、紧张型（25.5%）、持续型（7.3%）、梳齿型（7.3%）和暂停型（5.4%）等5种类型。记录深度在208～1855（829.0±328.1）μm之间，最佳频率在16.7～75.6（38.9±15.7）kHz之间，最小阈值在5～74（34.7±13.6）dB SPL之间，阈上10dB SPL潜伏期在5.0～27.5（15.2±3.9）ms之间。最佳频率随记录深度的增加而增大(r=0.9578，P<0.001)；记录的54个频率调谐曲线（FTCs）均为开放型，其中52个为单峰型，2个为双峰型。52个单峰型FTC的Q10-dB值介于1.56～31.61之间，并且大部分是狭窄型（Q10-dB值>5），占69.2%（36/52），少部分为宽阔型（Q10-dB值<5），占30.8%（16/52）。2个双峰型神经元FTC在低频处为宽阔型，高频处为狭窄型，Q10-dB值分别为1.95、8和2.89、6.51。共获得34个神经元的强度_发放率函数（RIFs），可分为单调型、非单调型和饱和型。结合先前所研究的FM蝙蝠——普通伏翼蝠（Pipistrllus abramus）下丘神经元的基本声反应特性，比较分析了CF/FM蝙蝠与FM蝙蝠下丘神经元的声反应差异及其行为学意义。

Natural auditory environment consists of multiple sound sources that are embedded in ambient strong and weak noise. For effective sound communication and signal analysis, animals must somehow extract biologically relevant signals from the inevitable interference of ambient noise. The present study examined how a weak noise may affect the amplitude sensitivity of neurons in the mouse central nucleus of the inferior colliculus (IC) which receives convergent excitatory and inhibitory inputs from both lower and higher auditory centers. Specifically, we studied the amplitude sensitivity of IC neurons using a probe (best frequency pulse) and a masker (weak noise) under simultaneous masking paradigm. For most IC neurons, weak noise masking increases the minimum threshold and decreases the number of impulses. Noise masking also increased the slope and decreased the dynamic range of the rate amplitude function of these IC neurons. The strength of this noise masking was greater at low than at high sound amplitudes. This variation in the amplitude sensitivity of IC neurons in the presence of the weak noise was mostly mediated through GABAergic inhibition. These data indicate that in the real world the ambient weak noise improves amplitude sensitivity of IC neurons through GABAergic inhibition while inevitably decreases the range of overall auditory sensitivity of IC neurons.

This study examined the effect of bicuculline application on the auditory response properties in the auditory cortex of the big brown bat, Eptesicus fuscus. All auditory cortical neurons studied discharged either 1-2 or 3-7 impulses to 4 ms sound stimuli. Cortical neurons with high best frequencies tended to have high minimum thresholds. Bicuculline application increased the number of impulses and shortened the response latencies of all cortical neurons as well as changing the discharge patterns of half of the cortical neurons studied. Bicuculline application raised the rate-intensity functions but lowered the latency-intensity functions to varying degrees. Threshold-frequency tuning curves (FTCs) were either V-shaped, upper threshold or double-peaked. Threshold-FTCs and impulse-FTCs were mirror-images of each other. Bicuculline application expanded and raised the impulse-FTCs but lowered the threshold-FTCs, resulting in significantly decreased Qn values. Threshold^FTCs of cortical neurons determined within an orthogonally inserted electrode were very similar and expanded FTCs during bicuculline application were also very similar. Possible mechanisms for the contribution of GABAergic inhibition to shaping these response properties of cortical neurons are discussed.

自由声场条件下，以强度为神经元最小阈值阈上5dB，时程分别为40、60、80和100ms的纯音作为前掩蔽声，观察和记录了不同时程弱前掩蔽声对小鼠（Mus musculus Km）下丘神经元发放和声强处理的影响。实验记录到154个神经元，对其中的104个神经元做了不同时程掩蔽声影响的测试。结果发现：掩蔽声对神经元放电率的抑制作用在时间上表现为前抑制（41%）、后抑制（9%）和全抑制（50%）三种类型。改变掩蔽声时程时，大部分神经元（72%）的抑制类型不发生改变，但少部分神经元（28%）随振蔽声时程的增加，大量的后抑制类型转变为前抑制或全抑制类型。此外超过一半的神经元（58.06%）其工、强度-放电率函数曲线随掩蔽声时程的改变而发生转变，主要表现为单调型向饱和型转变及饱和型向非单调型转变，这种转变并不随掩蔽声时程增加表现出规律性的变化。结果表明，前掩蔽作用于下丘神经元声反应的时间城和强度城时具有不均衡性，推测不同时程弱前掩蔽激活的抑制性输入能分化性调制下丘神经元声反应特性。