The quantum light-cone fluctuations in flat spacetimes with compactified spatial dimensions or with boundaries are examined. The discussion is based upon a model in which the source of the underlying metric fluctuations is taken to be quantized linear perturbations of the gravitational field. General expressions are derived, in the transverse trace-free gauge, for the summation of graviton polarization tensors, and for vacuum graviton two-point functions. Because of the fluctuating light cone, the flight time of photons between a source and a detector may be either longer or shorter than the light propagation time in the background classical spacetime. We calculate the mean deviations from the classical propagation time of photons due to the changes in the topology of the flat spacetime. These deviations are in general larger in the directions in which topology changes occur and are typically of the order of the Planck time, but they can get larger as the travel distance increases.

A spherical black-hole global-monopole system in thermal equilibrium is examined from the perspective of a grand canonical ensemble in which the temperature and surface area are fixed at a finite boundary. Using the Euclidean action with constraints eliminated, we investigate the thermodynamics of the system. It is shown that there exists a stable thermal equilibrium for the system in the ensemble. A comparison with ordinary black holes under equivalent boundary conditions indicates that if such a system exists, it will not decay spontaneously to a black hole without a global monopole.

We discuss the random motion of charged test particles driven by quantum electromagnetic fluctuations at finite temperature in both the unbounded flat space and flat spacetime with a reflecting boundary and calculate the mean squared fluctuations in the velocity and position of the test particle. We show that typically the random motion driven by the quantum fluctuations is one order of magnitude less significant than that driven by thermal noise in the unbounded flat space. However, in the flat space with a reflecting plane boundary, the random motion of quantum origin can become much more significant than that of thermal origin at very low temperature.

We consider a multilevel hydrogen atom in interaction with the quantum electromagnetic field and separately calculate the contributions of the vacuum fluctuation and radiation reaction to the rate of change of the mean atomic energy of the atom for uniform acceleration. It is found that the acceleration disturbs the vacuum fluctuations in such a way that the delicate balance between the contributions of vacuum fluctuation and radiation reaction that exists for inertial atoms is broken, so that the transitions to higher-lying states from ground state are possible even in vacuum. In contrast to the case of an atom interacting with a scalar field, the contributions of both electromagnetic vacuum fluctuations and radiation reaction to the spontaneous emission rate are affected by the acceleration, and furthermore the contribution of the vacuum fluctuations contains a nonthermal acceleration-dependent correction, which is possibly observable.

We discuss how compactified extra dimensions may have potentially observable effects which grow as the compactification scale decreases. This arises because of lightcone fluctuations in the uncompactified dimensions which can result in the broadening of the spectral lines from distant sources. We analyze this effect in a five dimensional model, and argue that data from gamma ray burst sources require the compactification length to be greater than about 105cm in this model.