目的探索微创切除垂体腺瘤的手术方法。方法对52例垂体腺瘤采用经鼻中隔蝶窦入路切除术。结果此种术式减少了手术创伤，缩短了手术路径，且不影响美观。结论经鼻中隔蝶窦切除垂体腺瘤安全有效，创伤小。是值得选择的一种手术方法。

将14～15天的胚胎脊髓组织移植到成年wistar大鼠半横断脊髓损伤腔，术后l～6月，通过爬坡、网格板走步、Tarlov运动分级和电生理的检查，评价损伤脊髓的功能恢复程度。在移植组动物，术后可见后肢运动功能逐渐恢复。6个月时，恢复的程度接近正常水平。对照组运动功能检查未见明显的改善。结果提示，胚胎脊髓组织移植在一定程度上有助于损伤脊髓的功能恢复。

本文应用生长抑素、5--羟色胺\P物质，胶质酸性蛋白的抗体，通过免疫细胞化学反应，对胚胎脊髓组织移植后的细胞构筑特征进行了观察。结果发现，移植后2--6个月的胚胎脊髓组织内分布有与上述抗体相应的免疫阳性神经元及神经纤维。在移植组织与宿主脊髓融合差的情况下，移植界面可见胶质酸性蛋白免疫反应明显增强。研究表明，免疫细胞化学方法可反映移植组织的生长分化程度，并可显示移植部位的细胞构筑特征。

A model of hyperosmotic opening of the blood-brain barrier(BBB)was successfully made by infusion of 1.4M mannitol into the internal carotid artery of rabbit. We selected lanthanum nitrate as a tracer. Ultrastructural changes of hyperosmotic opening of the BBB were observed through injection of lanthanum nitrate into blood vessels or through impregnation of small blocks of brain tissue in lanthanum solution. Electron microscopy showed that lanthanum nitrate passed through the opening of endothelial tight junction from the blood into the subendothelial layers and the extracellular spaces of the brain, or from the outside into the inside of blood vessels. The data suggest that the morphological basis of osmotic opening of BBB is the reversible widening of the tight junctions between endothelial cells, and that lanthanum nitrate infusion has an advantage over block impregnation.