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韩铭钧, 任克, 赵仲春, 张曦彤, 张汉国, 徐克
,-0001,():
-1年11月30日
目的 考查中药抗癌剂复方莪术油肝动脉栓塞治疗肝癌的疗效和意义。方法 用莪术油、鸦胆子油和碘油配制成复方莪术油,经肝动脉栓塞治疗54例原发性肝癌。结果 治疗后肿瘤平均缩小率39.2%。l、2年生存率分别为72%和29.4%。无因治疗引起肝功恶化和骨髓抑制现象。部分患者治疗后肝功能明显改善。结论 复方莪术油作为一种新的中药肝动脉栓塞剂治疗肝癌具有肯定的疗效。这种油性中药制剂具有抗癌,低毒,栓塞和留滞于肿瘤局部的突出特点。这些特点使它有很大的优势成为肝癌介入治疗的较为理想的栓塞剂。
肝肿瘤, 栓塞, 莪术油, 鸦胆子油
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韩铭钧, Ming-Jun Han, Han-Guo Zhao, Ke Ren, Dong-Chun Zhao, Ke Xu, Xi-Tong Zhang
Cardiovasc Intervent Radiol (1997)20:125-127,-0001,():
-1年11月30日
Purpose: To study the value of partial splenic embolization (PSE) for the treatment of hypersplenism in patients undergoing embolization of hepatocellular carcinoma (HCC). Methods: Transcatheter hepatic arterial embolization (THAE) combined with PSE was performed in 30 patients with HCC complicating liver cirrhosis, portal hypertension, and hypersplenism. Gelfoam sponge was used as the embolic material for PSE and limited to 100-150 pieces. Results: More than 50% of splenic parenchyma was infarcted in 27 patients. Leukopenia and thrombocytopenia were corrected by PSE in 25 of 27 patients with hypersplenism. In 26 patients with esophageal varices, including 5 patients with bleeding, no rebleeding occurred during a 6-17 month follow-up. Hypersplenism was not corrected in 2 of 3 patients whose infarcted splenic parenchyma was less than 50%. No splenic abscesses or other severe complications were observed. Of the 30 patients treated, 19 are still alive after 1 year. Conclusions: THAE combined with PSE is a safe and effective measure for patients with HCC.
Hepatic neoplasm-Embolization,, therapeutic-Splenic embolization
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