Two coordination polymers (2a and 2b) containing dinuclear zinc(II) macrocyclic components have been unexpectedly obtained when pyrazine and 2-methylpyrazine were used to react with dinuclear zinc(II) macrocyclic complexes 1a and 1b, respectively. The X-ray crystal structural study indicated that the coordination environment around each Zn(II) atom in 2 is a five-coordinated distorted pyramid in which the apical position is occupied by a bridging formate anion, unlocalized, in an end to end fashion. The formate group acts as a bidentate bridging ligand to link two adjacent macrocyclic units forming a chain polymer. In addition, Hbonding interactions are observed in the crystal packing of 2a and 2b, which could be described as two-dimensional networks.

Reaction between 4-aminopyridine and a dinuclear zinc(II) component of a Robson macrocyclic ligand has resulted in the formation of a molecular ladder element motif. X-ray single crystal structural analysis indicates that two pyridine rings are assembled at the same direction of the macrocycle, which are placed in a nearly parallel way via

Twenty-six new hydrophilic chiral 2-alkoxy-1,4-butanediamine platinum (II) complexes having a seven-membered ring structure between a bidentate carrier ligand and a platinum atom have been synthesized and most of them were evaluated for their in vitro cytotoxicity toward A549 human non-small cell lung carcinoma and HCT-116 human colon cancer cell lines. The cytotoxicities of platinum complexes are related to the nature of the carrier ligand and leaving group. Complex 50b, viz. cis-dichloro[(2R)-ethoxy-1,4-butanediamine] platinum (II), exhibits the greatest potency among those 21 tested platinum complexes in both cell lines.

A novel 1D neutral coordination polymer, {[Cu(dtmp)(dmf)Cl2]dmf}n (1) (dtmp=1,6-di(triazole-1-yl-methyl)-4-methylphenol, dmf=dimethyl formamide) was synthesized by reacting CuCl2 Æ 2H2O with the dtmp ligand. The crystal and molecular structure of the complex was determined by X-ray diffraction, in which the coordination geometry around the copper center is slightly distorted trigonal bypyramidal. One-dimensional chains have been formed through the metal and the ligand via oordination bonds, which are assembled further into a two-dimensional network by inter-chain synergic π-π stacking and hydrogen bonding.

The condensation between sodium 2,6-diformyl-4-X-phenolate (X=Cl, CH3) with the reduced 1:1 Schiff base of 2,2',2"-tris (aminoethyl) amine (tren) and 2-formylfuran (or benzaldehyde) followed by in situ transmetallation with copper(II) perchlorate results in the production of four novel tetranuclear copper(II) complexes of 2:2 macrocyclic Schiff bases with functional pendant-arms (H2L1-4), which have been spectroscopically characterized. A typical complex (1) has been structurally studied by X-ray diffraction. In the cation of complex 1, [Cu4L1Cl2(OH)2]2+, a chair-shaped Cu4O4 core with two μ3-hydroxide groups inside is composed of two kinds of crystallographicall ndependent Cu(II) atoms, while each possesses a configuration of a distorted square pyramid. The four metal atoms are in an approximate parallelogram. Two pendant-arms, mono-dentatively bonding to their adjacent metal atoms, lie in the 'trans' position of the macrocycle. The variable temperature magnetic susceptibility of 1 has been measured in a temperature rang 4-300K. The best fitting with a quasi-butterfly magnetostructural model shows antiferromagnetic exchanges within this compound, with Jbb=-270.8cm-1, Jwb1=-40.3cm-1 and Jwb2=-37.5cm-1.