中国科技论文在线

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2006年06月26日

【期刊论文】Methylation of p16 CpG Islands Associated with Malignant Transformation of Gastric Dysplasia in a Population-Based Study

邓大君， Yu Sun， Dajun Deng， Wei-Cheng You， Hua Bai， Lian Zhang， Jing Zhou， Lin Shen， Jun-Ling Ma， Yu-Quan Xie， and Ji-You Li

Vol. 10, 5087-5093, August 1, 2004，-0001，（）：

-1年11月30日

摘要

Purpose: Inactivation of p16 by aberrant methylation of CpG islands is a frequent event in carcinomas and precancerouslesions of various organs, including the stomach. Theaim of this study is to investigate the relationship betweenp16 methylation and mali

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2006年06月26日

【期刊论文】Hypermethylation of metallothionein-3 CpG island in gastric carcinoma

邓大君， Dajun Deng，， Wa'el El-Rifai， Jiafu Ji， Budong Zhu， Paul Trampont， Jiyou Li， Michael F.Smith and Steven M.Powell

Carcinogenesis vol.24 no.1 pp. 25-29, 2003，-0001，（）：

-1年11月30日

摘要

The expression of metallothionein (MT)-3 is often markedly reduced in gastric carcinoma (GC). The molecular mechanism of this MT-3 downregulation is unknown. Transcriptional silencing of MT-3 by methylation of CpG island was investigated by nucleotide seq

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2006年06月26日

【期刊论文】Formation of N-(Nitrosomethyl)urea in Stomachs of Experimental Pigs and Human Volunteers Given Fish Sauce in Vivo

邓大君， Dajun Deng* and Huijun Xin

J. Agric. Food Chem. 2000, 48, 2495-2498，-0001，（）：

-1年11月30日

摘要

N-(Nitrosomethyl)urea (NMU) was characterized in carcinogenic nitrosated fish sauce recently (Denget al. J. Agric. Food Chem. 1998, 46, 202-205; Biomed. Environ. Sci. 1999, 12, 54-61). To studythe possibility of intragastric synthesis of NMU, experimental

Nitrosomethylurea， fish products， nitrosation， pig， human， gastric juice， stomach cancer， nitrosamide， nitroso compounds， nitrite， HPLC

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2006年06月26日

【期刊论文】INDUCTION OF GASTRIC INTRAEPITHELIAL NEOPLASIA OF GLANDULAR STOMACH OF MONGOLIAN GERBILS BY HELICOBACTER PYLORI

邓大君， ZHOU Pin，， GU Lian-kun， ZHOU Jing， WANG Ru-ming， ZHAO Zi-hou， DENG Da-jun*

Chinese Journal of Cancer Research 17 (3): 190-192, 2005，-0001，（）：

-1年11月30日

摘要

Objective: To setup an animal model of gastric carcinogenesis by Helicobacter pylori (Hp) for basic, preventionand therapeutic research of Hp-related diseases. Methods: 22 young male Mongolian gerbils were administrated withsuspension of Hp strain TN2 by

Helicobacter pylori， Mongolian gerbil， Gastric carcinogenesis， Intraepithelial neoplasia

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