您当前所在位置: 首页 > 学者

胡礼泉

  • 60浏览

  • 0点赞

  • 0收藏

  • 0分享

  • 62下载

  • 0评论

  • 引用

期刊论文

Apoptosis in rat erectile tissue induced by castration

胡礼泉Xin-Hua ZHANG Li-Quan HU Xin-Min ZHENG Shi-Wen LI

Asian J Androl 1999 Dec; 1:181-185,-0001,():

URL:

摘要/描述

Aim: To investigate the effect of androgen on the structure of corpus cavernosum. Methods: Thirty mature rats were randomized into 3 groups, i.e., simple castration, castration with testosterone (T) supplementation and sham-operated controls. One week after operation, the animals were sacrificed and corpora cavenosa harvested. Apoptosis was detected with the in situ end labeling (ISEL) techniques and DNA fragment analysis. Results: The apoptotic rate was 4.19% in the simple castrated rats, 0.2% in castrated rats supplemented with T and 0.14% in the controls. Significant difference was found between the simple castrates and other two groups (P<0.01). When comparing the T-supplementation group with the controls, there was no statistical difference (P>0.05). Conclusion: Castration induced apoptosis in rat corpus cavernosum, that could be prevented by T supplementation. It suggests that androgen plays an important role in maintaining the structure of corpus cavernosum.

版权说明:以下全部内容由胡礼泉上传于   2005年08月16日 00时21分56秒,版权归本人所有。

我要评论

全部评论 0

本学者其他成果

    同领域成果