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期刊论文
Flow-injection chemiluminescence detection for studying protein binding for drug with ultrafiltration sampling
Analytica Chimica Acta 468 (2002) 65-70，-0001，（）：
The novel flow chemiluminescence (CL) system for determination of pipemidic acid was proposed, which was based on the sensitizing effect of pipemidic acid on the CL oxidation of sulfite by KMnO4 in acid media. Combined with the technique of ultrafiltration, the flow-injection CL system was applied to study in vitro the bovine serum album (BSA) binding of pipemidic acid. The estimated association constant (K) and the number of the binding site (n) on one molecule of BSA were 8.81
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