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期刊论文
Enantioselective oxidation of racemic 1,2-propanediol to D-(-)-actic acid by Gluconobacter oxydans
Tetrabedron: Asmmetry 15(2004)1275-1277,-0001,():
Ghiconobacter oxydans DSM 2003 was firstly used in the production of (R)-2-hydroxy-proionic acid through microbial oxidation of recemic 1,2-propanediol. The biotransformation was processed with high enantionmeric excess (>99%) and near theoretical lyicld (48% of racemic 1,2-propanediol) when the substrate concentration was lower than 20g/L. When the substrate concentration was increased. maintaining the pH at 6.0 helped to improve the enantionselectivity.
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