-
37浏览
-
0点赞
-
0收藏
-
0分享
-
138下载
-
0评论
-
引用
期刊论文
Oxidative Reactivity of S-Nitrosoglutathione with Hantzsch 1,4-Dihydropyridine
,-0001,():
Nitric oxide (NO) is an endogenous compound of the body involved in a variety of biological processes,1 including immunity-regulating functions, physiological control of blood pressure, and neurotransmission. Authentic NO in vivo has only a 0.1 s half-life.2 Nitrosothiols (RSNO), which are formed in vivo from the reaction of NO with protein or nonprotein thiols, can increase the effective tissue half-life of NO.3 RSNO is commonly referred to as a NO-donor and is found in various biological systems, such as in human plasma, airways, white blood cells, and rat cerebellum.4 Nitrosoglutathione (GSNO) has been shown to be one of the most aboundant RSNOs,4c,5,6 e.g., 0.3μM in bronchial lavage fluid and 0.7μM in brain, and to exhibit depressor action.7
【免责声明】以下全部内容由[吴隆民]上传于[2005年02月24日 18时04分03秒],版权归原创者所有。本文仅代表作者本人观点,与本网站无关。本网站对文中陈述、观点判断保持中立,不对所包含内容的准确性、可靠性或完整性提供任何明示或暗示的保证。请读者仅作参考,并请自行承担全部责任。
本学者其他成果
同领域成果