雷初朝
一直从事动物遗传学的教学与研究工作,专业方向为动物遗传资源研究。
个性化签名
- 姓名:雷初朝
- 目前身份:
- 担任导师情况:
- 学位:
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学术头衔:
博士生导师, 教育部“新世纪优秀人才支持计划”入选者
- 职称:-
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学科领域:
家畜育种学
- 研究兴趣:一直从事动物遗传学的教学与研究工作,专业方向为动物遗传资源研究。
雷初朝,男,1968年11月生,汉族,湖南省常宁市人,教授,博士(后),博士生导师。入选2007年教育部“新世纪优秀人才支持计划”,2005.06入选西北农林科技大学首届“青年学术骨干人才支持计划”。2004.12-2006.12在第四军医大学生物学博士后流动站从事合作研究,2002.12获得西北农林科技大学动物遗传育种与繁殖专业博士学位,1997.07获得西北农林科技大学动物遗传育种专业硕士学位,1991.07-1994.08在湖南省衡东县职业中专学校任教,1991.07获得湖南农业大学农学学士学位。一直从事动物遗传学的教学与研究工作,专业方向为动物遗传资源研究。主讲课程为:《动物遗传学》(本科生),动物基因组学(博士研究生)。近5年来主持陕西省自然基金1项,校内课题5项,参与国家“863”项目2项,参与国家基金3项,发表研究论文60余篇,其中SCI论文10余篇(第一作者4篇)。2003年2月获得陕西省科技进步一等奖(第4完成人),2001年10月,获得陕西省高等学校科技进步一等奖(第2完成人)。已招收硕士研究生10人,毕业2人。
社会兼职:中国遗传学会会员,中国细胞生物学会会员,中国畜牧兽医学会畜禽遗传标记学分会会员,中国畜牧兽医学会动物遗传育种学分会会员。
课题项目:1、主持2007年度教育部“新世纪优秀人才支持计划”。2、主持2007年度西北农林科技大学科研专项。3、主持中国博士后基金(20060391016)。4、主持2005年度西北农林科技大学“青年学术骨干支持计划”。5. 主持陕西自然科学基金(2001SM14)。
获奖情况:1. 陕西地方黄牛遗传特征研究, 获得2003年陕西省科技进步一等奖, 排名第4。2. 陕西四个黄牛品种染色体研究, 获得2001年陕西高校科技进步一等奖, 排名第2。3. 动物遗传育种系列课程双螺旋教学模式研究, 获得2001年陕西省优秀教学成果二等奖, 排名第4。4. Y染色体多态性与中国黄牛起源和分类研究, 获得2001年陕西省第七届自然科学叁等优秀学术论文奖, 排名第1。5. 3个黄牛品种染色体的G带模式图研究, 获得2001年陕西省第七届自然科学叁等优秀学术论文奖, 排名第2。6.中国部分黄牛品种mtDNA遗传多态性研究, 获得2006年陕西省第九届自然科学一等优秀学术论文奖, 排名第1。
审稿情况:是国内外知名期刊如:Animal Genetics,Journal of Heredity,《动物学报》,《中国生物化学与分子生物学报》和《西北农林科技大学学报》(自然科学版)的审稿专家。
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【期刊论文】Association of IGF-I gene polymorphisms with milk yield and body size in Chinese dairy goats
雷初朝
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-1年11月30日
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雷初朝
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-1年11月30日
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【期刊论文】Genetic diversity of mitochondrial cytochrome b gene in Chinese native buffalo
雷初朝
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-1年11月30日
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【期刊论文】Multiple maternal origins of native modern and ancient horse populations in China
雷初朝
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-1年11月30日
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【期刊论文】Independent maternal origin of Chinese swamp buffalo (Bubalus bubalis)
雷初朝
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-1年11月30日
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【期刊论文】Genetic diversity and origin of Chinese cattle revealed by mtDNA D-loop sequence variation
雷初朝, Song-Jia Laia, , Yi-Ping Liua, *, Yan-Xing Liub, Xue-Wei Lia, Yong-Gang Yaoc
Molecular Phylogenetics and Evolution 38 (2006) 146-154,-0001,():
-1年11月30日
To determine the origin and genetic diversity of Chinese cattle, we analyzed the complete mtDNA D-loop sequences of 84 cattle from 14 breeds/populations from southwest and west China, together with the available cattle sequences in GenBank. Our results showed that the Chinese cattle samples converged into two main groups, which correspond to the two species Bos taurus and Bos indicus. Although a dominant lineage was clearly discerned in both B. taurus and B. indicus mtDNAs, network analysis of the lineages in each of the two species further revealed multiple clades that presented regional diVerence. The B. taurus samples in China could be grouped into clades T2, T3, and T4, whereas B. indicus harbored two clades I1 and I2. Age estimation of these discerned clades showed a time range of 14,100-44,500 years before present (YBP). The phylogenetic pattern of Chinese cattle was consistent with the recently described cattle matrilineal pool from northeast Asia, but suggested that B. indicus contributed more to the cattle from south and southwest China. The genetic diversity of Chinese cattle varied among the breeds studied.
Chinese cattle, mtDNA, D-loop, Genetic diversity, Origin
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【期刊论文】Polymorphisms of two Ychromosome microsatellites in Chinese cattle
雷初朝, Xin CAIa, Hong CHENab∗, ShanWANGa, Kai XUEa, Chuzhao LEIa
Genet. Sel. Evol. 38 (2006) 525-534,-0001,():
-1年11月30日
Two Y chromosome specific microsatellites UMN2404 and UMN0103 were genotyped and assessed for polymorphisms in a total of 423 unrelated males from 25 indigenous Chinese cattle breeds. Consistently, both microsatellites displayed specific indicine and taurine alleles in each bull examined. The indicine and taurine alleles were detected in 248 males (58.6%), and 175 males (41.4%), respectively, although these frequencies varied amongst different breeds examined. The indicine alleles dominated in the southern group (92.4%), while the taurine alleles dominated in the northern group (95.5%). Hainan Island was possibly the site for the origin of Chinese zebu, and Tibetan cattle were probably independently domesticated from another strain of Bos primigenius. The geographical distribution of these frequencies reveals a pattern of male indicine introgression and a hybrid zone of indicine and taurine cattle in China. The declining south-to-north and east-to-west gradient of male indicine introgression in China could be explained by historical data, geographical segregation and temperature and weather conditions.
Chinese cattle, taurine, indicine, genetic introgression, Y chromosome
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雷初朝, 陈宏, , ①, 杨公社, 宋林生, 雷雪芹, 孙维斌, 李瑞彪, 刘小林
遗传学报,2004,(1):57~62,-0001,():
-1年11月30日
对我国8个黄牛品种22个个体的mtDNA D-loop 区910 bp 全序列进行了分析。结果表明:8个黄牛品种 D-loop 区序列中,A+T 平均含量为61.65%;经比对,共检测到66个核苷酸多态位点,约占核苷酸总数的7.25%;D-loop 全序列突变类型有5种,即转换、颠换、插入、缺失转换与颠换共存,它们分别占核苷酸多态位点的81.82%、6.06%、7.57%、3.03%及1.52%。以欧洲牛mtKNA D-loop 全序列为标准,8个黄牛群体D-loop 的平均核苷酸变异率分3个层次:西镇牛、蒙古牛、黑折花牛及秦川牛的核苷酸变异率最低,分别为0.37%、0.44%、0.52%和0.66%;南阳牛与郏县红牛的核苷酸变异率居中,分中别为1.91%和2.02%;晋南牛与岳阳牛的核苷酸变异率最高,分别为4.47%和4.73%。中国黄牛品种内D-loop 区序列歧异度为0.55%~5.39%,品种间序列歧异度为1.21%~6.59%。在所测黄牛个体中,mtDNA D-loop 序列由19种单倍型组成,单倍型比列为86.36%,说明中国黄牛mtDNA 遗传多态性很丰富。由此构建了中国8个黄牛品种的NJ分子系统树,聚类分析表明:所测黄牛的mtDNA D-loop 序列表现为3个单倍型组,从而提示中国黄牛可能有3个母系起源,以普通牛起源和瘤牛起源为主。
黄牛, 线粒体DNA, D-loop, 多态性, 单倍型, 起源
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【期刊论文】Study on Mitochondrial DNA D-loop Polymorphism in Chinese Donkeys
雷初朝, LEI Chu-Zhao, CHEN Hong, , ①, YANG Gong-She, SUN Wei-Bin, LEI Xue-Qin, GE Qing-Lan, WANG Zhao-Feng, Lü Ning, GAO Xue, HOU Wen-Tong
Acta Genetica Sinica, May 2005, 32 (5): 481~486,-0001,():
-1年11月30日
The mitochondrial DNA (mtDNA) D-loop sequences with 399 bp in 26 individuals from 5 donkey breeds in China were analyzed. Aligned by Clustal W software, the results showed that 23 polymorphic nucleotide sites and only transition with the percentage of 5.76% in 399 bp were observed. In reference to mtDNA D-loop sequences of European domestic donkey as a control, the average percentage of mtDNA D-loop nucleotide variation in 5 Chinese donkey breeds was 1.80%. The average percentages of D-loop nucle otide variation from Liangzhou donkey (LZ), Yunan donkey (YN), Guanzhong donkey (GZ), Xinjiang donkey (XJ) and Jiamidonkey (JM) WERE 0.35%, 125%, 2.30, 2.91% and 2.20% respectively. The average sequence divergence estimated from D-loop sequences varied from 0.25%~5.01% within breeds and 4.51%~5.51% among breeds, respectively, demonstrating that there existed rather abundant mitochondrial enetic diversity in Chinese donkeys. Comparisons of the 26 sequences revealed 11 mitochondrial haplotypes: the percentage of haplotype was 42.31%. This phenomenon demonstrated that the mitochondrial genetic diversity in Chinese donkey breeds is being reduced. It is urgent to protect the genetic resources of Chinese donkey. The molecular phylogenetic tree of mtDNA D-loop sequenceds in 5 Chinese donkey breeds, 6 sequences of Asian wild ass (Equus asinus kiang, Equus asinus kulan, Equus asinus hemionus;) and 4 sequences of European domestic donkeys from GenBank was constructed by Neighbor-Joining method. It was the first time proved in molecular level that the origin of Chinese donkey breds was from African wild ass (Equue africanus africanus somaliensis), not from Asian wild ass as bescribed in the paper.
donkey, mitochondrial DNA, D-loop, polymorphism, haplotype, origin
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