In this paper, an accurate and route method was developed to quantitative determine daidzein, genistein, glycitein, daidzin, glycitin, 6 "-Oacetyldaidzin, 6" -O-acetylglycitin and 6”-O-acetylgenistin contents in selected high and low isoflavones in nutrition supplements by on line liquid chromatography–atmospheric pressure chemical ionisation mass spectrometry (LC-APCI-MS). Improved extraction and hydrolysis methods of the isoflavones from three nutrition supplements were also studied and a rapid extraction method was developed. Comparison of different MS2 and MS3 spectra of isoflavones and some unknown compounds were also explored and proposed pathway fragments of nine isoflavones were first systematically suggested.

Analytical Milli high-speed counter-current chromatography (HSCCC) was used for the selection and optimization of the two-phase solvent system to separate flavonoids from the extracts of the seeds of Oroxylum indicum. The optimum solvent system obtained from Milli-CCC was also the best solvent system for preparative HSCCC and led to the successful separation of two crude flavonoids from the seeds of O. indicum by Lab/Prep (laboratory preparative) HSCCC using different sized coils. Four flavonoids were isolated by preparative HSCCC: baicalein-7-O-diglucoside (25.0mg, 92% purity), baicalein-7-o-glucoside (50.4mg; 95% purity), baicalein (75mg; purity 98%) and chrysin (100 mg; purity 98%).

Four flavonoids, chrysin, baicalein, baicalein-7-O-glucoside, baicalein-7-O-diglucoside (Oroxylin B) and one unknown flavonoid have been isolated and purified for the first time in the seeds of Oroxylum indicum by high-speed counter-current chromatography with a two-phase solvent system composed of chloroform-methanol-water (8:10:5, v/v). Then, 50 mg baicalein-7-O-glucoside, 10.5mg baicalein-7-O-diglucoside, 4.5mg chrysin-7-O-diglucoside, 25 mg baicalein and 45 mg chrysin could be obtained after injecting 20 mg/ml sample extract ten times and their purities were 96, 90, 85, 95 and 98%, respectively. All these constituents were identified by high-performance liquid chromatography–mass spectrometry and nuclear magnetic resonance.

采用分光光度法，以重铬酸钾为显色剂，在1mol/L盐酸介质中不经分离测定复方乙酰水扬酸片、去痛片中非那西丁含量，其平均回收率和相对标准偏差分别为100.6%，0.36%；100.1%，0.26%，结果较满意。

对无水氯化钙与液氨的反应产物（简称CAC）的稳定性进行了研究，提出了改进CAC稳定性新技术—碳化法原位成盐包膜技术。研究表明：碳化法原位成盐包膜可以较好地提高CAC的稳定性。包膜CAC的最佳条件是：当CAC呈膏状且不流动时通以流速为120mL/min的CO2.3～5min对CAC进行微粒包膜，经造粒后进行大颗粒二次包膜。二次包膜后的CAC在25～35℃范围可以较稳定存在，且包膜后的CAC含氮量可以稳定在31%以上。大颗粒包膜CAC对其稳定性的增强更有利。