噬菌蛭弧菌具有裂解病原菌、净化水体的功效，从海洋环境中分离到4 株Bh04 系列蛭弧菌，对其生长条件进行了测定，同时研究了它们对61 株菌株的裂解能力。结果表明，在1%～3%的盐度范围内，蛭弧菌均可生长，最适盐度为3%！；在15～ 30！温度条件下蛭弧菌也可生长，但最适培养温度为20_25；只有在使用活的宿主菌的培养条件下，蛭弧菌才能生长。4株蛭弧菌分别可裂解21、24、4 0、43 株菌，各占总试验菌数（61）的344%、393%、656%和70 5%。4 株蛭弧菌一起，则可裂解55 菌株，占总试验菌株的902%。研究结果揭示了蛭弧菌在消除海洋环境中有害细菌方面的潜在应用价值。

噬菌蛭弧菌具有裂解病原菌的特殊功效，可以用作生物净化因子。本实验从海洋环境中分离到4 株Bh04系列蛭弧菌(Bh04-4, Bh04-41a, Bh04-A+ 和 Bh04-1f)。以41株弧菌为蛭弧菌的宿主菌，本文研究了蛭弧菌对海产品中常见弧菌的裂解消除能力，以探索其对由弧菌所引起的食物中毒等流行性传染疾病的预防效果。实验结果表明，41株弧菌中共有36菌株可被4株蛭弧菌(Bh04-4, Bh04-41a, Bh04-A+和Bh04-1f)中的任一株所裂解，占总试验菌株的87.8%；对副溶血弧菌、非01 非0139 群霍乱弧菌、溶藻胶弧菌这三种常见致病弧菌的裂解率分别达88.9%、83.3%、81.8%。本研究结果揭示了蛭弧菌作为生物消除剂在由弧菌所引起的食物中毒等流行性传染疾病的防治方面有潜在应用价值。

从海洋环境中分离出4 株蛭弧菌(Bdellovibrio sp.)，并对34 株九孔鲍 (Haliotis diversicolor) 苗细菌性病原进行了裂解试验。结果表明，Bh04-4、Bh04-41a、Bh04-A+和Bh04-1f 等4 株蛭弧菌分别可裂解11株、13 株、22 株和28 株病原菌裂解率为32.4%、38.2%、64.7%和87.5% 4；株共同作用则可裂解32 株病原菌，裂解率高达94.1%。研究结果展示了应用蛭弧菌控制九孔鲍苗细菌性病原的可行性。

Outbreaks of mass mortality among cultured postlarvae of abalone Haliotis diversicolor supertexta aged between 7 and 30 days occurred since 2002 on the south coast of China. Among 24 bacterial strains isolated from diseased abalone postlarvae on 2216E Marine and TCBS agar plates during an outbreak in July 2003, 23 were avirulent whilst a predominant strain (designated as strain 2) was highly virulent to postlarvae with an LD50 value under 1.0×103 colony forming units (CFU) ml−1. All the moribund/dead postlarvae exhibited the same gross symptoms as that observed in natural outbreaks. The same bacteria could be re-isolated from postlarvae after bacterial challenge using 2216E Marine and TCBS agar plates. API analysis identified it to be Vibrio parahaemolyticus with 99% confidence. 16S and ITS rDNA sequencing analysis also revealed it to be highly homologous with Vibrio parahaemolyticus. Kanagawa reaction and PCR amplification of TDH gene on strain 2 proved to be negative. Antibiotic susceptibility tests showed that strain 2 exhibited 56.25% of susceptibility to chemotherapeutic agents tested, and was resistant to penicillin G, amikacin, trimethoprim–sulfamethoxazole, tetracycline, ciprofloxacin, novobiocin and neomycin. Results in this study reveal that V. parahaemolyticus strain 2 is an infectious agent to abalone postlarvae in South China.