高建新
生物医学工程——医学图像处理,生物力学。
个性化签名
- 姓名:高建新
- 目前身份:
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- 学位:
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学术头衔:
博士生导师
- 职称:-
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学科领域:
固体力学
- 研究兴趣:生物医学工程——医学图像处理,生物力学。
高建新,男,1964年出生,教授,博士生导师。1980.9-1984.7,浙江大学力学系本科,获固体力学理学学士学位;1984.9-1989.12,清华大学工程力学系攻读硕士、博士,获固体力学工学博士学位;1989.12-1994.10,在上海城市建设学院建筑工程系任教;1994.10-至今,在同济大学生物医学工程研究所(现生命科学与技术学院生物医学工程系)从事科研与教学工作,期间于1998年3月至1999年3月,在香港科技大学机械系做访问学者;2001年1月至2004年1月,在英国帝国理工学院计算机系从事合作科研工作;2004年10月至今,在英国萨利大学生物医学工程中心从事合作科研工作。
研究方向:生物医学工程——医学图像处理,生物力学。从90年代中期开始涉足医学图像处理和生物力学的交叉研究领域,曾开发了包括完整的牙齿与颞骨的复杂多连通人体结构的三维有限元建模技术,为口腔修复方案的生物力学定量评价奠定了基础。同时还开发建立了一套对口腔修复中的冠体、嵌体、贴面进行仿真设计的实验系统。在英国帝国理工学院计算机系皇家医学信息计算研究实验室从事的科研合作工作具体为:医学图像配准,磁共振心脏灌注图像的定量测量和分析,心脏磁共振速度和相位图像的测量处理,三维超声心脏灌注图像的测量处理等。目前在英国萨利大学生物医学工程中心从事的工作为:骨整合技术及其在高位截瘫病人假肢安装中的相关技术的研究,假肢邻接器的失效保护装置的优化设计、分析与制造。目前是中国力学学会会员,《实验力学》学报编辑部成员,国际医学磁共振学会(ISMRM)会员。在国内外学术刊物和会议上已发表论文50余篇。
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435
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成果数
8
高建新, Zhengyuan Caoa, *, Jianxin Gaoa, Shaode Gua, Guohong Zhangb
Optics and Lasers in Engineering 43(2005)1127-1136,-0001,():
-1年11月30日
We report a method measuring 3-Ddisplacement of cambered mirror for cryogenic optical system using white light speckle photography with double light sources and double cameras. Data acquiring and processing based on a digital image processing system is described. The 3-Ddisplacement and displacement vector distributions in two low-temperature ranges are measured.
3-Ddisplacement, White light speckle photography, Digital image processing, Cambered mirror, Cryogenic optical system
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【期刊论文】Predictive Cardiac Motion Modeling and Correction With Partial Least Squares Regression
高建新, Nicholas A. Ablitt, Jianxin Gao, Jennifer Keegan, Lars Stegger, David N. Firmin, and Guang-Zhong Yang*
IEEE TRANSACTIONS ON MEDICAL IMAGING, VOL. 23, NO.10, OCTOBER 2004,-0001,():
-1年11月30日
Respiratory-induced cardiac deformation is a major problem for high-resolution cardiac imaging. This paper presents a new technique for predictive cardiac motion modeling and correction, which uses partial least squares regression to extract intrinsic relationships between three-dimensional (3-D) cardiac deformation due to respiration and multiple one-dimensional real-time measurable surface intensity traces at chest or abdomen. Despite the fact that these surface intensity traces can be strongly coupled with each other but poorly correlated with respiratory-induced cardiac deformation, we demonstrate how they can be used to accurately predict cardiac motion through the extraction of latent variables of both the input and output of the model. The proposed method allows cross-modality reconstruction of patient specific models for dense motion field prediction, which after initial modeling can be used for real-time prospective motion tracking or correction. Detailed numerical issues related to the technique are discussed and the effectiveness of the motion and deformation modeling is validated with 3-D magnetic resonance data sets acquired from ten asymptomatic subjects covering the entire respiratory range.
Cardiac imaging,, image registration,, partial least squares,, PLSR,, predictive motion modeling,, respiratory motion correction.,
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【期刊论文】Virtual Tagging: Numerical Considerations and Phantom Validation
高建新, Sharmeen Masood, Jianxin Gao, and Guang-Zhong Yang*
IEEE TRANSACTIONS ON MEDICAL IMAGING, VOL. 21, NO.9, SEPTEMBER 2002,-0001,():
-1年11月30日
This paper presents a virtual tagging framework for measuring, as well as visualising, myocardial deformation using magnetic resonance (MR) velocity imaging. Tagging grids are allocated artificially according to the deformation gradient with varying shapes and densities. The control points are then deformed such that the difference between the induced deformation velocity and that of actually measured MR data is minimum. A full three-dimensional implementation of the technique combined with the mass conservation constraint is provided. Numerical considerations of applying the proposed framework and different optimization strategies have been investigated with both simulated and phantom experiments. The accuracy of the technique in terms of following material deformation is compared with that of conventional tagging technique. Index Terms-Finite-element analysis, magnetic resonance (MR) tagging, mass conservation, myocardial deformation, myocardial velocity mapping, strain analysis.
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【期刊论文】Deformation Modelling Based on PLSR for Cardiac Magnetic Resonance Perfusion Imaging
高建新, Jianxin Gao, Nick Ablitt, Andrew Elkington, and Guang-Zhong Yang,
MICCAI 2002, LNCS 2488, pp. 612-619, 2002.,-0001,():
-1年11月30日
This paper introduces a novel approach to deformation modeling based on partial-least-squares-regression and its application to the registration of first-pass magnetic resonance perfusion image sequences. The method relies on the extraction of intrinsic correlations between the latent factors of both the input and output signals for deriving a simple yet accurate deformation model. The strength of the technique has been demonstrated with both numerically simulated data sets and a myocardial perfusion study which involves nine patients with known coronary artery disease. The method represents a step forward for the commonly used principal component analysis for salient motion feature extraction. The proposed technique should be applicable to studies that involve deformation prediction such as motion adaptive radiotherapy and imaging, where the deformation of the target organ can be predicted from externally measurable signals.
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高建新
同济大学学报,1997,26(1):98~103,-0001,():
-1年11月30日
通过空彤彤态函敷的引入,将数字圈像(嵌斑)档是搜索方法进一步推广。提出丁敷字图像相是分析法在这一方击中,把对桩秽厦其各十导敷分量独立进行的相先进代变为叶变形彤态画敷的系数进行相是遗代,从而既简化丁速代过程,更妾现丁整十空彤埽的直接剥量(计算)。典型的实验蛄秉验证丁进一方法的可行性。
实验力学, 数字散斑, 相差笼折, 变形形态
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高建新, 周辛庚, 章玮宝, 龚欣芸
实验力学,1996,11(3):334~338,-0001,():
-1年11月30日
本文应用数字图像测量系统.对砼试件在成形早期最初26小时的变形场进行了非接触的定量测量,得到了砼成形早期收缩应变随时间变化的曲线。整个测量过程简便直接,表明数字图像测量方法完全可用来对砼结构的位移场进行非接触的精密测量,在配备了相应的光学观察仪器后,也可用来测量一般的应变场,从而特为土建结构的定量测试提供新的有力手段。
数字图像,, 相关测量,, 砼成表,, 砼变形
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【期刊论文】3D shape reconstruction of teeth by shadow speckle correlation method
高建新, Jianxin Gaoa, Wei Xua, Jianping Gengb
Optics and Lasers in Engineering 44(2006)455-465,-0001,():
-1年11月30日
This paper presents a new method for 3D shape reconstruction in computer-aided dental prosthetics. A specklegram is projected onto the tooth to be measured. This shadow speckle image is recorded and then processed by a digital image correlation method, which enables the computation of 2D shapes based on the similar principle of shadow moire method. By repeating the procedure for all the sides, i.e., one crown and several side surfaces, local 2D shapes can be measured precisely. Afterwards, these local 2D profiles are merged to form a 3D model, during which certain constraints such as the widths along perpendicular directions are introduced to guide the process. As the height information within an entire image field is recorded instantly, it has the potential to be employed in an intra-oral environment, which would make the patient feel more comfortable during the restoration process. In vitro experiments were carried out on gypsum teeth models and the results proved the effectiveness of the proposed method.
Shadow speckle, Digital image correlation, Dental prosthetics, 3D shape reconstruction, Shape measurement
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高建新, 周辛庚
力学学报,1995,27(6):724~731,-0001,():
-1年11月30日
应用图像识别与变分学原理,对数字散斑相关方法作了理论阐述,导出了测量物体表面变形场的一般过程,将力学中的变形测量问题转化为单纯的数值计算问题,避免了传统光测方法与干涉条纹有关的一系列困难。初步的实验结果表明,该方法在工程实际现场、高速冲击动态过程、细观力学变形过程以及变形测量的自动化等方面都有广泛的应用潜力,从而为光测力学拓展应用领域、实现自动化测量展现了新的前景。
数字散斑,, 相关,, 变形测量,, 图像处理,, 细观力学
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